The crystal structure of wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000988503
Cuypers, M.G., Slavish, J.P., Rankovic, Z., White, S.W.To be published.
Experimental Data Snapshot
Starting Model: experimental
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Entity ID: 1 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
Polymerase acidic protein | 197 | Influenza A virus (A/California/04/2009(H1N1)) | Mutation(s): 0  Gene Names: PA EC: 3.1 | ||
UniProt | |||||
Find proteins for C3W5S0 (Influenza A virus (strain swl A/California/04/2009 H1N1)) Explore C3W5S0  Go to UniProtKB:  C3W5S0 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | C3W5S0 | ||||
Sequence AnnotationsExpand | |||||
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Ligands 4 Unique | |||||
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ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
QQ4 Query on QQ4 | E [auth A] | Hexa Vinylpyrrolidone K15 C36 H56 N6 O6 OFPQNVWJHZVWCZ-CMPUJJQDSA-N | |||
Y5V (Subject of Investigation/LOI) Query on Y5V | D [auth A] | 5-hydroxy-N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-2-(2-methylphenyl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide C21 H21 N3 O5 KEGVYPYJMJWBAI-UHFFFAOYSA-N | |||
SO4 Query on SO4 | F [auth A], G [auth A], H [auth A] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L | |||
MN Query on MN | B [auth A], C [auth A] | MANGANESE (II) ION Mn WAEMQWOKJMHJLA-UHFFFAOYSA-N |
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 89.591 | α = 90 |
b = 89.591 | β = 90 |
c = 133.076 | γ = 90 |
Software Name | Purpose |
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PHENIX | refinement |
PHENIX | refinement |
XDS | data reduction |
Aimless | data scaling |
MOLREP | phasing |