KRAS4b WT 1-185 bound to GDP-Mg2+
Betts, L., Rossman, K.L.To be published.
Experimental Data Snapshot
Entity ID: 1 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
GTPase KRas | 185 | Homo sapiens | Mutation(s): 1  Gene Names: KRAS, KRAS2, RASK2 EC: 3.6.5.2 | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P01116 (Homo sapiens) Explore P01116  Go to UniProtKB:  P01116 | |||||
PHAROS:  P01116 GTEx:  ENSG00000133703  | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P01116 | ||||
Sequence AnnotationsExpand | |||||
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Ligands 3 Unique | |||||
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ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
GDP (Subject of Investigation/LOI) Query on GDP | D [auth A], G [auth B] | GUANOSINE-5'-DIPHOSPHATE C10 H15 N5 O11 P2 QGWNDRXFNXRZMB-UUOKFMHZSA-N | |||
GOL Query on GOL | E [auth A] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N | |||
MG (Subject of Investigation/LOI) Query on MG | C [auth A], F [auth B] | MAGNESIUM ION Mg JLVVSXFLKOJNIY-UHFFFAOYSA-N |
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 84.313 | α = 90 |
b = 84.313 | β = 90 |
c = 41.733 | γ = 120 |
Software Name | Purpose |
---|---|
PHENIX | refinement |
XDS | data reduction |
XDS | data scaling |
PHENIX | phasing |
Funding Organization | Location | Grant Number |
---|---|---|
National Institutes of Health/National Cancer Institute (NIH/NCI) | United States | 5R01CA223495 |