Crystal structure of human serum albumin and ruthenium PZA complex adduct
Gong, W.J., Wang, Y., Bai, H.H.To be published.
Experimental Data Snapshot
Entity ID: 1 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
Albumin | 585 | Homo sapiens | Mutation(s): 0  Gene Names: ALB, GIG20, GIG42, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696/PRO1341 | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P02768 (Homo sapiens) Explore P02768  Go to UniProtKB:  P02768 | |||||
PHAROS:  P02768 GTEx:  ENSG00000163631  | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P02768 | ||||
Sequence AnnotationsExpand | |||||
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Ligands 5 Unique | |||||
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ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
PLM Query on PLM | B [auth A], C [auth A], D [auth A], E [auth A], F [auth A] | PALMITIC ACID C16 H32 O2 IPCSVZSSVZVIGE-UHFFFAOYSA-N | |||
PZA (Subject of Investigation/LOI) Query on PZA | H [auth A], I [auth A] | PYRAZINE-2-CARBOXAMIDE C5 H5 N3 O IPEHBUMCGVEMRF-UHFFFAOYSA-N | |||
RU Query on RU | J [auth A], K [auth A] | RUTHENIUM ION Ru BPEVHDGLPIIAGH-UHFFFAOYSA-N | |||
CL Query on CL | L [auth A], M [auth A], N [auth A] | CHLORIDE ION Cl VEXZGXHMUGYJMC-UHFFFAOYSA-M | |||
NO Query on NO | G [auth A] | NITRIC OXIDE N O ODUCDPQEXGNKDN-UHFFFAOYSA-N |
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 182.441 | α = 90 |
b = 38.326 | β = 105.1 |
c = 95.039 | γ = 90 |
Software Name | Purpose |
---|---|
PHENIX | refinement |
HKL-2000 | data scaling |
PDB_EXTRACT | data extraction |
HKL-2000 | data reduction |
PHENIX | phasing |
Funding Organization | Location | Grant Number |
---|---|---|
National Natural Science Foundation of China (NSFC) | China | 62075118 |
National Natural Science Foundation of China (NSFC) | China | 21671125 |
National Science Foundation (NSF, China) | China | 21601112 |