Download MendeleyInfluenza A/California/07/2009(H1N1) endonuclease in complex with flavonoid-like compound
Radilova, K., Kotacka, T., Kozisek, M., Kral, M., Machara, A., Reiberger, R., Brynda, J.To be published.
8PPX
Influenza A/California/07/2009(H1N1) endonuclease in complex with flavonoid-like compound
- PDB DOI: https://doi.org/10.2210/pdb8PPX/pdb
- Classification: VIRAL PROTEIN
- Organism(s): Influenza A virus (A/California/07/2009(H1N1))
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2023-07-10 Released: 2025-01-15
- Funding Organization(s): European Union (EU)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.50 Å
- R-Value Free: 0.258
- R-Value Work: 0.227
- R-Value Observed: 0.228
Starting Model: experimental
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wwPDB Validation 3D Report Full Report
This is version 1.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Polymerase acidic protein | 186 | Influenza A virus (A/California/07/2009(H1N1)) | Mutation(s): 0 Gene Names: PA EC: 3.1 |  | |
UniProt | |||||
Find proteins for C3W5X6 (Influenza A virus) Explore C3W5X6 Go to UniProtKB: C3W5X6 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | C3W5X6 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 4 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| 85W (Subject of Investigation/LOI) Query on 85W | E [auth A] | 5-oxidanyl-2-[4,5,7-tris(oxidanyl)naphthalen-2-yl]-1H-pyrimidin-6-one C14 H10 N2 O5 ZRYLCHISGNOMOQ-UHFFFAOYSA-N |  | ||
| MN Query on MN | B [auth A] | MANGANESE (II) ION Mn WAEMQWOKJMHJLA-UHFFFAOYSA-N |  | ||
| CL Query on CL | D [auth A] | CHLORIDE ION Cl VEXZGXHMUGYJMC-UHFFFAOYSA-M |  | ||
| MG Query on MG | C [auth A] | MAGNESIUM ION Mg JLVVSXFLKOJNIY-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.50 Å
- R-Value Free: 0.258
- R-Value Work: 0.227
- R-Value Observed: 0.228
- Space Group: P 64 2 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 73.96 | α = 90 |
| b = 73.96 | β = 90 |
| c = 128.18 | γ = 120 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| XSCALE | data scaling |
| XDS | data reduction |
| MOLREP | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2025-01-15 Deposition Author(s): Radilova, K., Brynda, J.
| Funding Organization | Location | Grant Number |
|---|---|---|
| European Union (EU) | European Union | LX22NPO5103 |
Revision History (Full details and data files)
- Version 1.0: 2025-01-15
Type: Initial release
