Download MendeleySubstrate Promiscuity, Crystal Structure, and Application of a Plant UDP-Glycosyltransferase UGT74AN3
Huang, W., Zhang, X., Li, J., Lv, J., Wang, Y., He, Y., Song, J., Agren, H., Jiang, R., Deng, Z., Long, F.(2024) ACS Catal 14: 475-488
8WRJ
glycosyltransferase UGT74AN3
- PDB DOI: https://doi.org/10.2210/pdb8WRJ/pdb
- Classification: TRANSFERASE
- Organism(s): Catharanthus roseus
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2023-10-15 Released: 2024-01-24
- Funding Organization(s): National Natural Science Foundation of China (NSFC)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.85 Å
- R-Value Free: 0.252
- R-Value Work: 0.209
- R-Value Observed: 0.211
Starting Model: in silico
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This is version 1.0 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Glycosyltransferase | 474 | Catharanthus roseus | Mutation(s): 0 EC: 2.4.1 |  | |
UniProt | |||||
Find proteins for W8JMV4 (Catharanthus roseus) Explore W8JMV4 Go to UniProtKB: W8JMV4 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | W8JMV4 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| UDP Query on UDP | C [auth A] | URIDINE-5'-DIPHOSPHATE C9 H14 N2 O12 P2 XCCTYIAWTASOJW-XVFCMESISA-N |  | ||
| 6JI (Subject of Investigation/LOI) Query on 6JI | B [auth A] | 5-[(1R,2S,4R,6R,7R,10S,11S,14S,16R)-14-hydroxy-7,11-dimethyl-3-oxapentacyclo[8.8.0.02,4.02,7.011,16]octadecan-6-yl]pyran-2-one C24 H32 O4 ATLJNLYIJOCWJE-CWMZOUAVSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.85 Å
- R-Value Free: 0.252
- R-Value Work: 0.209
- R-Value Observed: 0.211
- Space Group: P 21 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 46.022 | α = 90 |
| b = 53.005 | β = 90 |
| c = 200.795 | γ = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| XDS | data reduction |
| Aimless | data scaling |
| PHENIX | phasing |
Entry History & Funding Information
Deposition Data
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Natural Science Foundation of China (NSFC) | China | -- |
Revision History (Full details and data files)
- Version 1.0: 2024-01-24
Type: Initial release
