Download MendeleyCrystal structure of Purine nucleoside phosphorylase from Trichomonas vaginalis (inosine bound)
Ung, A.R., Lovell, S., Liu, L., Battaile, K.P.To be published.
9MJQ
Crystal structure of Purine nucleoside phosphorylase from Trichomonas vaginalis (inosine bound)
- PDB DOI: https://doi.org/10.2210/pdb9MJQ/pdb
- Classification: TRANSFERASE
- Organism(s): Trichomonas vaginalis G3
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2024-12-16 Released: 2025-01-22
- Funding Organization(s): National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID), National Institutes of Health/Office of the Director
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.20 Å
- R-Value Free: 0.159
- R-Value Work: 0.130
- R-Value Observed: 0.132
Starting Model: in silico
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This is version 1.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Purine nucleoside phosphorylase, putative | 244 | Trichomonas vaginalis G3 | Mutation(s): 0 Gene Names: TVAG_454490 |  | |
UniProt | |||||
Find proteins for A2EU62 (Trichomonas vaginalis (strain ATCC PRA-98 / G3)) Explore A2EU62 Go to UniProtKB: A2EU62 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | A2EU62 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| NOS (Subject of Investigation/LOI) Query on NOS | B [auth A] | INOSINE C10 H12 N4 O5 UGQMRVRMYYASKQ-KQYNXXCUSA-N |  | ||
| CL Query on CL | C [auth A], D [auth A], E [auth A] | CHLORIDE ION Cl VEXZGXHMUGYJMC-UHFFFAOYSA-M |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.20 Å
- R-Value Free: 0.159
- R-Value Work: 0.130
- R-Value Observed: 0.132
- Space Group: H 3 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 92.821 | α = 90 |
| b = 92.821 | β = 90 |
| c = 130.152 | γ = 120 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| Aimless | data scaling |
| XDS | data reduction |
| PHASER | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2025-01-22 Deposition Author(s): Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID) | United States | 75N93022C00036 |
| National Institutes of Health/Office of the Director | United States | S10OD030394 |
Revision History (Full details and data files)
- Version 1.0: 2025-01-22
Type: Initial release
