4OTJ

The complex of murine cyclooxygenase-2 with a conjugate of indomefathin and podophyllotoxin, N-{(succinylpodophyllotoxinyl)but-4-yl}-2-{1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl}acetamide

Changes made to a PDB entry after its initial release are considered to be either “major” or “minor”. The latest minor version of each major version is available as a file download. More information about the PDB versioning is available.

Version Number	Version Date	Version Type/Reason	Version Change	Revised CIF Category
1.0	2015-04-08	Initial release
1.1	2016-12-07		Database references
1.2	2017-02-15		Database references		Download
2.0	2020-07-29	Remediation / Carbohydrate remediation	Advisory, Atomic model, Data collection, Derived calculations, Structure summary	atom_site, atom_site_anisotrop, chem_comp, entity, pdbx_branch_scheme, pdbx_chem_comp_identifier, pdbx_entity_branch, pdbx_entity_branch_descriptor, pdbx_entity_branch_link, pdbx_entity_branch_list, pdbx_entity_nonpoly, pdbx_nonpoly_scheme, pdbx_struct_assembly_gen, pdbx_struct_conn_angle, pdbx_unobs_or_zero_occ_atoms, struct_asym, struct_conn, struct_site, struct_site_gen
2.1	2023-09-20		Advisory, Data collection, Database references, Refinement description, Structure summary	chem_comp, chem_comp_atom, chem_comp_bond, database_2, pdbx_initial_refinement_model, pdbx_unobs_or_zero_occ_atoms
2.2	2024-11-06		Structure summary	pdbx_entry_details, pdbx_modification_feature	Download

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.