Annotations: 1B8H

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B	d1b8hb1	Alpha and beta proteins (a+b)	DNA clamp	DNA clamp	DNA polymerase processivity factor	gp45 sliding clamp	(Escherichia phage RB69 ) [TaxId: 12353 ],	SCOPe (2.08)
A	d1b8ha1	Alpha and beta proteins (a+b)	DNA clamp	DNA clamp	DNA polymerase processivity factor	gp45 sliding clamp	(Escherichia phage RB69 ) [TaxId: 12353 ],	SCOPe (2.08)
C	d1b8hc1	Alpha and beta proteins (a+b)	DNA clamp	DNA clamp	DNA polymerase processivity factor	gp45 sliding clamp	(Escherichia phage RB69 ) [TaxId: 12353 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	DNA clamp	8036417	3000780	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	DNA clamp	8036416	3000780	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	DNA clamp	8036416	3000780	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	DNA clamp	8036417	3000780	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	DNA clamp	8036417	3000780	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	DNA clamp	8036416	3000780	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	DNA_PPF_1	e1b8hB1	A: a+b two layers	X: DNA clamp (From Topology)	H: DNA clamp (From Topology)	T: DNA clamp	F: DNA_PPF_1	ECOD (1.6)
B	gp45-slide_C	e1b8hB2	A: a+b two layers	X: DNA clamp (From Topology)	H: DNA clamp (From Topology)	T: DNA clamp	F: gp45-slide_C	ECOD (1.6)
A	DNA_PPF_1	e1b8hA1	A: a+b two layers	X: DNA clamp (From Topology)	H: DNA clamp (From Topology)	T: DNA clamp	F: DNA_PPF_1	ECOD (1.6)
A	gp45-slide_C	e1b8hA2	A: a+b two layers	X: DNA clamp (From Topology)	H: DNA clamp (From Topology)	T: DNA clamp	F: gp45-slide_C	ECOD (1.6)
C	DNA_PPF_1	e1b8hC1	A: a+b two layers	X: DNA clamp (From Topology)	H: DNA clamp (From Topology)	T: DNA clamp	F: DNA_PPF_1	ECOD (1.6)
C	gp45-slide_C	e1b8hC2	A: a+b two layers	X: DNA clamp (From Topology)	H: DNA clamp (From Topology)	T: DNA clamp	F: gp45-slide_C	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	3.70.10.10	Alpha Beta	Box	Proliferating Cell Nuclear Antigen		CATH (4.3.0)
A	3.70.10.10	Alpha Beta	Box	Proliferating Cell Nuclear Antigen		CATH (4.3.0)
C	3.70.10.10	Alpha Beta	Box	Proliferating Cell Nuclear Antigen		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C	PF09116	gp45 sliding clamp, C terminal (gp45-slide_C)	gp45 sliding clamp, C terminal	Members of this family are essential for the interaction of the gp45 sliding clamp with the corresponding polymerase. They adopt a DNA clamp fold, consisting of two alpha helices and two beta sheets - the fold is duplicated and has internal pseudo tw ...	Members of this family are essential for the interaction of the gp45 sliding clamp with the corresponding polymerase. They adopt a DNA clamp fold, consisting of two alpha helices and two beta sheets - the fold is duplicated and has internal pseudo two-fold symmetry [1].	Domain
A, B, C	PF02916	DNA polymerase processivity factor (DNA_PPF)	DNA polymerase processivity factor	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
D	DNA POLYMERASE fragment	catalytic activity, acting on DNA DNA-directed DNA polymerase activity DNA polymerase activity catalytic activity, acting on a nucleic acid transferase activity nucleotidyltransferase activity catalytic activity transferase activity, transferring phosphorus-containing groups DNA binding binding organic cyclic compound binding nucleic acid binding nuclease activity hydrolase activity, acting on ester bonds catalytic activity, acting on DNA DNA-directed DNA polymerase activity DNA polymerase activity catalytic activity, acting on a nucleic acid transferase activity nucleotidyltransferase activity catalytic activity transferase activity, transferring phosphorus-containing groups DNA binding binding organic cyclic compound binding nucleic acid binding nuclease activity hydrolase activity, acting on ester bonds 3'-5' exonuclease activity hydrolase activity exonuclease activity nucleoside phosphate binding nucleotide binding heterocyclic compound binding small molecule binding cation binding ion binding metal ion binding	nucleobase-containing compound metabolic process DNA replication metabolic process primary metabolic process DNA metabolic process macromolecule metabolic process nucleic acid metabolic process cellular biosynthetic process cellular metabolic process viral DNA genome replication viral life cycle nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid biosynthetic process nucleobase-containing compound metabolic process DNA replication metabolic process primary metabolic process DNA metabolic process macromolecule metabolic process nucleic acid metabolic process cellular biosynthetic process cellular metabolic process viral DNA genome replication viral life cycle nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid biosynthetic process biosynthetic process viral genome replication viral process bidirectional double-stranded viral DNA replication cellular process DNA biosynthetic process	-
A, B, C	DNA POLYMERASE PROCESSIVITY COMPONENT	enzyme regulator activity DNA polymerase processivity factor activity enzyme activator activity molecular function activator activity molecular function regulator activity	nucleobase-containing compound metabolic process DNA replication metabolic process primary metabolic process DNA metabolic process macromolecule metabolic process nucleic acid metabolic process viral gene expression viral process viral transcription cellular biosynthetic process cellular metabolic process viral DNA genome replication viral life cycle nucleobase-containing compound metabolic process DNA replication metabolic process primary metabolic process DNA metabolic process macromolecule metabolic process nucleic acid metabolic process viral gene expression viral process viral transcription cellular biosynthetic process cellular metabolic process viral DNA genome replication viral life cycle nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid biosynthetic process biosynthetic process viral genome replication cellular process DNA biosynthetic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
D	IPR036397	Ribonuclease H superfamily	Homologous Superfamily
D	IPR006134	DNA-directed DNA polymerase, family B, multifunctional domain	Domain
D	IPR034749	DNA-directed DNA polymerase T4 type	Family
D	IPR006172	DNA-directed DNA polymerase, family B	Family
D	IPR043502	DNA/RNA polymerase superfamily	Homologous Superfamily
D	IPR006133	DNA-directed DNA polymerase, family B, exonuclease domain	Domain
D	IPR050240	DNA polymerase type-B	Family
D	IPR017964	DNA-directed DNA polymerase, family B, conserved site	Conserved Site
D	IPR012337	Ribonuclease H-like superfamily	Homologous Superfamily
D	IPR023211	DNA polymerase, palm domain superfamily	Homologous Superfamily
A, B, C	IPR046938	DNA clamp superfamily	Homologous Superfamily
A, B, C	IPR046389	Sliding clamp	Family
A, B, C	IPR004190	DNA polymerase processivity factor	Domain
A, B, C	IPR015200	Sliding clamp, C-terminal	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.