1CEL
THE THREE-DIMENSIONAL CRYSTAL STRUCTURE OF THE CATALYTIC CORE OF CELLOBIOHYDROLASE I FROM TRICHODERMA REESEI
External Resource: Annotation
- Domain Annotation: SCOP/SCOPe Classification
- Domain Annotation: SCOP2 Classification
- Domain Annotation: ECOD Classification
- Domain Annotation: CATH
- Protein Family Annotation
- Gene Ontology: Gene Product Annotation
- InterPro: Protein Family Classification
- Protein Modification Annotation
- Structure Motif: Primary M-CSA Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d1cela_ | All beta proteins | Concanavalin A-like lectins/glucanases | Concanavalin A-like lectins/glucanases | Glycosyl hydrolase family 7 catalytic core | Cellobiohydrolase I (cellulase, Endoglucanase I, CBH1) | Hypocrea jecorina (Trichoderma reesei ) [TaxId: 51453 ], | SCOPe (2.08) |
B | d1celb_ | All beta proteins | Concanavalin A-like lectins/glucanases | Concanavalin A-like lectins/glucanases | Glycosyl hydrolase family 7 catalytic core | Cellobiohydrolase I (cellulase, Endoglucanase I, CBH1) | Hypocrea jecorina (Trichoderma reesei ) [TaxId: 51453 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | Glyco_hydro_7 | e1celA1 | A: beta sandwiches | X: jelly-roll | H: Concanavalin A-like | T: Concanavalin A-like lectins/glucanases | F: Glyco_hydro_7 | ECOD (1.6) |
B | Glyco_hydro_7 | e1celB1 | A: beta sandwiches | X: jelly-roll | H: Concanavalin A-like | T: Concanavalin A-like lectins/glucanases | F: Glyco_hydro_7 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 2.70.100.10 | Mainly Beta | Distorted Sandwich | 1,4-Beta-D-Glucan Cellobiohydrolase I | Chain A | CATH (4.3.0) |
B | 2.70.100.10 | Mainly Beta | Distorted Sandwich | 1,4-Beta-D-Glucan Cellobiohydrolase I | Chain A | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00840 | Glycosyl hydrolase family 7 (Glyco_hydro_7) | Glycosyl hydrolase family 7 | - | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily | Homologous Superfamily | |
IPR000254 | Cellulose-binding domain, fungal | Domain | |
IPR037019 | Glycoside hydrolase family 7, catalytic domain superfamily | Homologous Superfamily | |
IPR001722 | Glycoside hydrolase, family 7 | Family | |
IPR035971 | Cellulose-binding domain superfamily | Homologous Superfamily |
Structure Motif Annotation: Mechanism and Catalytic Site Atlas M-CSA Database Homepage
Chains | Enzyme Name | Description | Catalytic Residues |
---|---|---|---|
cellulose 1,4-beta-cellobiosidase (non-reducing end) M-CSA #444 | Cellobiohydrolase enzymes depolymerise cellulose into its fundamental repeating unit of two glucose molecules (cellobiose). These enzymes are key components of fungal cellulase multienzyme systems; together with randomly-acting endo-1,4-beta-glucanases (which cut internal beta-1,4-glucosidic bonds) they hydrolyse cellulose via a processive mechanism, forming cellobiose as a major product. Cellobiose is then converted by beta-glucosidases to glucose; the latter product may further be fermented to ethanol or other liquid fuels and chemicals. | EC: 3.2.1.91 (PDB Primary Data) |