1E6Z

CHITINASE B FROM SERRATIA MARCESCENS WILDTYPE IN COMPLEX WITH CATALYTIC INTERMEDIATE

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B	d1e6zb1	All beta proteins	WW domain-like	Carbohydrate binding domain	Carbohydrate binding domain	Chitinase B, C-terminal domain	(Serratia marcescens ) [TaxId: 615 ],	SCOPe (2.08)
B	d1e6zb2	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	(Trans)glycosidases	Type II chitinase	Chitinase B, catalytic domain	(Serratia marcescens ) [TaxId: 615 ],	SCOPe (2.08)
B	d1e6zb3	Alpha and beta proteins (a+b)	FKBP-like	Chitinase insertion domain	Chitinase insertion domain	Chitinase B	(Serratia marcescens ) [TaxId: 615 ],	SCOPe (2.08)
A	d1e6za1	All beta proteins	WW domain-like	Carbohydrate binding domain	Carbohydrate binding domain	Chitinase B, C-terminal domain	(Serratia marcescens ) [TaxId: 615 ],	SCOPe (2.08)
A	d1e6za2	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	(Trans)glycosidases	Type II chitinase	Chitinase B, catalytic domain	(Serratia marcescens ) [TaxId: 615 ],	SCOPe (2.08)
A	d1e6za3	Alpha and beta proteins (a+b)	FKBP-like	Chitinase insertion domain	Chitinase insertion domain	Chitinase B	(Serratia marcescens ) [TaxId: 615 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	Carbohydrate binding domain-like	8032614	3001641	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	(Trans)glycosidases	8032616	3000313	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	(Trans)glycosidases	8032616	3000313	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Chitinase insertion domain	8032617	3000666	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	(Trans)glycosidases	8032616	3000313	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	(Trans)glycosidases	8032616	3000313	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Chitinase insertion domain	8032617	3000666	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Carbohydrate binding domain-like	8032614	3001641	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	CBM_5_12	e1e6zB2	A: beta meanders	X: WW domain-like	H: Carbohydrate binding domain (From Topology)	T: Carbohydrate binding domain	F: CBM_5_12	ECOD (1.6)
B	ChiA	e1e6zB1	A: a+b two layers	X: FKBP-like	H: Chitinase insertion domain (From Topology)	T: Chitinase insertion domain	F: ChiA	ECOD (1.6)
B	Glyco_hydro_18	e1e6zB3	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: Glyco_hydro_18	ECOD (1.6)
A	CBM_5_12	e1e6zA2	A: beta meanders	X: WW domain-like	H: Carbohydrate binding domain (From Topology)	T: Carbohydrate binding domain	F: CBM_5_12	ECOD (1.6)
A	ChiA	e1e6zA1	A: a+b two layers	X: FKBP-like	H: Chitinase insertion domain (From Topology)	T: Chitinase insertion domain	F: ChiA	ECOD (1.6)
A	Glyco_hydro_18	e1e6zA3	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: Glyco_hydro_18	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	3.20.20.80	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Glycosidases	CATH (4.3.0)
B	3.10.50.10	Alpha Beta	Roll	Chitinase A	domain 3	CATH (4.3.0)
B	2.10.10.20	Mainly Beta	Ribbon	Seminal Fluid Protein PDC-109 (Domain B)	Carbohydrate-binding module superfamily 5/12	CATH (4.3.0)
A	3.20.20.80	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Glycosidases	CATH (4.3.0)
A	3.10.50.10	Alpha Beta	Roll	Chitinase A	domain 3	CATH (4.3.0)
A	2.10.10.20	Mainly Beta	Ribbon	Seminal Fluid Protein PDC-109 (Domain B)	Carbohydrate-binding module superfamily 5/12	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF00704	Glycosyl hydrolases family 18 (Glyco_hydro_18)	Glycosyl hydrolases family 18	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	CHITINASE B	binding carbohydrate binding chitin binding carbohydrate derivative binding chitinase activity hydrolase activity, acting on glycosyl bonds hydrolase activity, hydrolyzing O-glycosyl compounds hydrolase activity catalytic activity	carbohydrate derivative catabolic process catabolic process carbohydrate derivative metabolic process chitin metabolic process aminoglycan catabolic process macromolecule catabolic process glucosamine-containing compound catabolic process amino sugar catabolic process aminoglycan metabolic process amino sugar metabolic process metabolic process cellular process macromolecule metabolic process chitin catabolic process carbohydrate derivative catabolic process catabolic process carbohydrate derivative metabolic process chitin metabolic process aminoglycan catabolic process macromolecule catabolic process glucosamine-containing compound catabolic process amino sugar catabolic process aminoglycan metabolic process amino sugar metabolic process metabolic process cellular process macromolecule metabolic process chitin catabolic process glucosamine-containing compound metabolic process carbohydrate metabolic process polysaccharide metabolic process polysaccharide catabolic process carbohydrate catabolic process primary metabolic process	cellular anatomical structure extracellular region

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR029070	Chitinase insertion domain superfamily	Homologous Superfamily
A, B	IPR001579	Glycosyl hydrolase family 18, active site	Active Site
A, B	IPR017853	Glycoside hydrolase superfamily	Homologous Superfamily
A, B	IPR003610	Carbohydrate binding module family 5/12	Domain
A, B	IPR050314	Glycosyl Hydrolase Family 18	Family
A, B	IPR001223	Glycoside hydrolase family 18, catalytic domain	Domain
A, B	IPR011583	Chitinase II/V-like, catalytic domain	Domain
A, B	IPR036573	Carbohydrate-binding module superfamily 5/12	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.