Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad1f4aa1 All beta proteins Immunoglobulin-like beta-sandwich beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain beta-Galactosidase, domains 2 and 4 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Ad1f4aa3 All beta proteins Galactose-binding domain-like Galactose-binding domain-like beta-Galactosidase/glucuronidase, N-terminal domain beta-Galactosidase (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Ad1f4aa4 All beta proteins Supersandwich Galactose mutarotase-like beta-Galactosidase, domain 5 beta-Galactosidase, domain 5 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Ad1f4aa5 Alpha and beta proteins (a/b) TIM beta/alpha-barrel (Trans)glycosidases beta-glycanases beta-Galactosidase, domain 3 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Bd1f4ab1 All beta proteins Immunoglobulin-like beta-sandwich beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain beta-Galactosidase, domains 2 and 4 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Bd1f4ab3 All beta proteins Galactose-binding domain-like Galactose-binding domain-like beta-Galactosidase/glucuronidase, N-terminal domain beta-Galactosidase (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Bd1f4ab4 All beta proteins Supersandwich Galactose mutarotase-like beta-Galactosidase, domain 5 beta-Galactosidase, domain 5 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Bd1f4ab5 Alpha and beta proteins (a/b) TIM beta/alpha-barrel (Trans)glycosidases beta-glycanases beta-Galactosidase, domain 3 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Cd1f4ac1 All beta proteins Immunoglobulin-like beta-sandwich beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain beta-Galactosidase, domains 2 and 4 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Cd1f4ac3 All beta proteins Galactose-binding domain-like Galactose-binding domain-like beta-Galactosidase/glucuronidase, N-terminal domain beta-Galactosidase (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Cd1f4ac4 All beta proteins Supersandwich Galactose mutarotase-like beta-Galactosidase, domain 5 beta-Galactosidase, domain 5 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Cd1f4ac5 Alpha and beta proteins (a/b) TIM beta/alpha-barrel (Trans)glycosidases beta-glycanases beta-Galactosidase, domain 3 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Dd1f4ad1 All beta proteins Immunoglobulin-like beta-sandwich beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain beta-Galactosidase, domains 2 and 4 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Dd1f4ad3 All beta proteins Galactose-binding domain-like Galactose-binding domain-like beta-Galactosidase/glucuronidase, N-terminal domain beta-Galactosidase (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Dd1f4ad4 All beta proteins Supersandwich Galactose mutarotase-like beta-Galactosidase, domain 5 beta-Galactosidase, domain 5 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Dd1f4ad5 Alpha and beta proteins (a/b) TIM beta/alpha-barrel (Trans)glycosidases beta-glycanases beta-Galactosidase, domain 3 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B Superfamily(Trans)glycosidases 8037663 3000313 SCOP2B (2022-06-29)
ASCOP2B Superfamilygalactose-binding domain-like 8037655 3000087 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyGalactose mutarotase-like 8037659 3000035 SCOP2B (2022-06-29)
ASCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055209 3002047 SCOP2B (2022-06-29)
ASCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055462 3002047 SCOP2B (2022-06-29)
BSCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055209 3002047 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyGalactose mutarotase-like 8037659 3000035 SCOP2B (2022-06-29)
BSCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055462 3002047 SCOP2B (2022-06-29)
BSCOP2B Superfamily(Trans)glycosidases 8037663 3000313 SCOP2B (2022-06-29)
BSCOP2B Superfamilygalactose-binding domain-like 8037655 3000087 SCOP2B (2022-06-29)
CSCOP2B Superfamilygalactose-binding domain-like 8037655 3000087 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyGalactose mutarotase-like 8037659 3000035 SCOP2B (2022-06-29)
CSCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055462 3002047 SCOP2B (2022-06-29)
CSCOP2B Superfamily(Trans)glycosidases 8037663 3000313 SCOP2B (2022-06-29)
CSCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055209 3002047 SCOP2B (2022-06-29)
DSCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055462 3002047 SCOP2B (2022-06-29)
DSCOP2B Superfamilygalactose-binding domain-like 8037655 3000087 SCOP2B (2022-06-29)
DSCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055209 3002047 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyGalactose mutarotase-like 8037659 3000035 SCOP2B (2022-06-29)
DSCOP2B Superfamily(Trans)glycosidases 8037663 3000313 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AGlyco_hydro_2_Ne1f4aA1 A: beta sandwichesX: jelly-rollH: Concanavalin A-likeT: Galactose-binding domain-likeF: Glyco_hydro_2_NECOD (1.6)
AGlyco_hydro_2e1f4aA2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: Glyco_hydro_2ECOD (1.6)
ADUF4981e1f4aA3 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: DUF4981ECOD (1.6)
ABgal_small_Ne1f4aA4 A: beta sandwichesX: Glycosyl hydrolase domain-likeH: supersandwich (From Topology)T: supersandwichF: Bgal_small_NECOD (1.6)
AGlyco_hydro_2_Ce1f4aA5 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Glyco_hydro_2_CECOD (1.6)
BGlyco_hydro_2_Ne1f4aB1 A: beta sandwichesX: jelly-rollH: Concanavalin A-likeT: Galactose-binding domain-likeF: Glyco_hydro_2_NECOD (1.6)
BGlyco_hydro_2e1f4aB2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: Glyco_hydro_2ECOD (1.6)
BDUF4981e1f4aB3 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: DUF4981ECOD (1.6)
BBgal_small_Ne1f4aB4 A: beta sandwichesX: Glycosyl hydrolase domain-likeH: supersandwich (From Topology)T: supersandwichF: Bgal_small_NECOD (1.6)
BGlyco_hydro_2_Ce1f4aB5 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Glyco_hydro_2_CECOD (1.6)
CGlyco_hydro_2_Ne1f4aC1 A: beta sandwichesX: jelly-rollH: Concanavalin A-likeT: Galactose-binding domain-likeF: Glyco_hydro_2_NECOD (1.6)
CGlyco_hydro_2e1f4aC2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: Glyco_hydro_2ECOD (1.6)
CDUF4981e1f4aC3 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: DUF4981ECOD (1.6)
CBgal_small_Ne1f4aC4 A: beta sandwichesX: Glycosyl hydrolase domain-likeH: supersandwich (From Topology)T: supersandwichF: Bgal_small_NECOD (1.6)
CGlyco_hydro_2_Ce1f4aC5 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Glyco_hydro_2_CECOD (1.6)
DGlyco_hydro_2_Ne1f4aD1 A: beta sandwichesX: jelly-rollH: Concanavalin A-likeT: Galactose-binding domain-likeF: Glyco_hydro_2_NECOD (1.6)
DGlyco_hydro_2e1f4aD2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: Glyco_hydro_2ECOD (1.6)
DDUF4981e1f4aD3 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: DUF4981ECOD (1.6)
DBgal_small_Ne1f4aD4 A: beta sandwichesX: Glycosyl hydrolase domain-likeH: supersandwich (From Topology)T: supersandwichF: Bgal_small_NECOD (1.6)
DGlyco_hydro_2_Ce1f4aD5 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Glyco_hydro_2_CECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D
PF02836Glycosyl hydrolases family 2, TIM barrel domain (Glyco_hydro_2_C)Glycosyl hydrolases family 2, TIM barrel domainThis family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.Domain
A, B, C, D
PF00703Glycosyl hydrolases family 2 (Glyco_hydro_2)Glycosyl hydrolases family 2This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.Domain
A, B, C, D
PF02837Glycosyl hydrolases family 2, sugar binding domain (Glyco_hydro_2_N)Glycosyl hydrolases family 2, sugar binding domainThis family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities and has a jelly-roll fold. The domain binds the sugar moiety during the sugar-hydrolysis reaction.Domain
A, B, C, D
PF16353Beta-galactosidase, domain 4 (LacZ_4)Beta-galactosidase, domain 4This entry represents domain 4 found in beta-galactosidase [1] and it is organised in a jelly-roll type barrel (Rutkiewicz-Krotewicz M. et al. Crystals 2018, 8(1), 13, https://doi.org/10.3390/cryst8010013).Domain
A, B, C, D
PF02929Beta galactosidase small chain (Bgal_small_N)Beta galactosidase small chainThis domain comprises the small chain of dimeric beta-galactosidases EC:3.2.1.23. This domain is also found in single chain beta-galactosidase.Domain