1FM9
THE 2.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE HETERODIMER OF THE HUMAN RXRALPHA AND PPARGAMMA LIGAND BINDING DOMAINS RESPECTIVELY BOUND WITH 9-CIS RETINOIC ACID AND GI262570 AND CO-ACTIVATOR PEPTIDES.
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d1fm9a_ | All alpha proteins | Nuclear receptor ligand-binding domain | Nuclear receptor ligand-binding domain | Nuclear receptor ligand-binding domain | Retinoid-X receptor alpha (RXR-alpha) | human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
B [auth D] | d1fm9d_ | All alpha proteins | Nuclear receptor ligand-binding domain | Nuclear receptor ligand-binding domain | Nuclear receptor ligand-binding domain | Peroxisome proliferator activated receptor gamma, PPAR-gamma | human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2 Family | Nuclear receptor ligand-binding domain | 8026316 | 4001384 | SCOP2 (2022-06-29) |
A | SCOP2 Superfamily | Nuclear receptor ligand-binding domain | 8038695 | 3001442 | SCOP2 (2022-06-29) |
B [auth D] | SCOP2B Superfamily | Nuclear receptor ligand-binding domain | 8035649 | 3001442 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | Hormone_recep | e1fm9A1 | A: alpha arrays | X: Nuclear receptor ligand-binding domain (From Topology) | H: Nuclear receptor ligand-binding domain (From Topology) | T: Nuclear receptor ligand-binding domain | F: Hormone_recep | ECOD (1.6) |
B [auth D] | Hormone_recep_1 | e1fm9D1 | A: alpha arrays | X: Nuclear receptor ligand-binding domain (From Topology) | H: Nuclear receptor ligand-binding domain (From Topology) | T: Nuclear receptor ligand-binding domain | F: Hormone_recep_1 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 1.10.565.10 | Mainly Alpha | Orthogonal Bundle | Retinoid X Receptor | Retinoid X Receptor | CATH (4.3.0) |
B [auth D] | 1.10.565.10 | Mainly Alpha | Orthogonal Bundle | Retinoid X Receptor | Retinoid X Receptor | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00104 | Ligand-binding domain of nuclear hormone receptor (Hormone_recep) | Ligand-binding domain of nuclear hormone receptor | This all helical domain is involved in binding the hormone in these receptors. | Domain | |
B [auth D] | PF00104 | Ligand-binding domain of nuclear hormone receptor (Hormone_recep) | Ligand-binding domain of nuclear hormone receptor | This all helical domain is involved in binding the hormone in these receptors. | Domain |