Annotations: 1G2C

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1g2c.1	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	HRSV fusion protein core	(Human respiratory syncytial virus strain RSS-2 ) [TaxId: 11261 ],	SCOPe (2.08)
C	d1g2c.2	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	HRSV fusion protein core	(Human respiratory syncytial virus strain RSS-2 ) [TaxId: 11261 ],	SCOPe (2.08)
E	d1g2c.3	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	HRSV fusion protein core	(Human respiratory syncytial virus strain RSS-2 ) [TaxId: 11261 ],	SCOPe (2.08)
G	d1g2c.4	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	HRSV fusion protein core	(Human respiratory syncytial virus strain RSS-2 ) [TaxId: 11261 ],	SCOPe (2.08)
I	d1g2c.5	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	HRSV fusion protein core	(Human respiratory syncytial virus strain RSS-2 ) [TaxId: 11261 ],	SCOPe (2.08)
K	d1g2c.6	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	HRSV fusion protein core	(Human respiratory syncytial virus strain RSS-2 ) [TaxId: 11261 ],	SCOPe (2.08)
M	d1g2c.7	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	HRSV fusion protein core	(Human respiratory syncytial virus strain RSS-2 ) [TaxId: 11261 ],	SCOPe (2.08)
O	d1g2c.8	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	HRSV fusion protein core	(Human respiratory syncytial virus strain RSS-2 ) [TaxId: 11261 ],	SCOPe (2.08)
Q	d1g2c.9	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	HRSV fusion protein core	(Human respiratory syncytial virus strain RSS-2 ) [TaxId: 11261 ],	SCOPe (2.08)
S	d1g2c.a	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	HRSV fusion protein core	(Human respiratory syncytial virus strain RSS-2 ) [TaxId: 11261 ],	SCOPe (2.08)
U	d1g2c.b	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	HRSV fusion protein core	(Human respiratory syncytial virus strain RSS-2 ) [TaxId: 11261 ],	SCOPe (2.08)
W	d1g2c.c	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	HRSV fusion protein core	(Human respiratory syncytial virus strain RSS-2 ) [TaxId: 11261 ],	SCOPe (2.08)
B	d1g2c.1	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	HRSV fusion protein core	(Human respiratory syncytial virus strain RSS-2 ) [TaxId: 11261 ],	SCOPe (2.08)
D	d1g2c.2	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	HRSV fusion protein core	(Human respiratory syncytial virus strain RSS-2 ) [TaxId: 11261 ],	SCOPe (2.08)
F	d1g2c.3	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	HRSV fusion protein core	(Human respiratory syncytial virus strain RSS-2 ) [TaxId: 11261 ],	SCOPe (2.08)
H	d1g2c.4	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	HRSV fusion protein core	(Human respiratory syncytial virus strain RSS-2 ) [TaxId: 11261 ],	SCOPe (2.08)
J	d1g2c.5	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	HRSV fusion protein core	(Human respiratory syncytial virus strain RSS-2 ) [TaxId: 11261 ],	SCOPe (2.08)
L	d1g2c.6	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	HRSV fusion protein core	(Human respiratory syncytial virus strain RSS-2 ) [TaxId: 11261 ],	SCOPe (2.08)
N	d1g2c.7	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	HRSV fusion protein core	(Human respiratory syncytial virus strain RSS-2 ) [TaxId: 11261 ],	SCOPe (2.08)
P	d1g2c.8	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	HRSV fusion protein core	(Human respiratory syncytial virus strain RSS-2 ) [TaxId: 11261 ],	SCOPe (2.08)
R	d1g2c.9	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	HRSV fusion protein core	(Human respiratory syncytial virus strain RSS-2 ) [TaxId: 11261 ],	SCOPe (2.08)
T	d1g2c.a	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	HRSV fusion protein core	(Human respiratory syncytial virus strain RSS-2 ) [TaxId: 11261 ],	SCOPe (2.08)
V	d1g2c.b	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	HRSV fusion protein core	(Human respiratory syncytial virus strain RSS-2 ) [TaxId: 11261 ],	SCOPe (2.08)
X	d1g2c.c	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	HRSV fusion protein core	(Human respiratory syncytial virus strain RSS-2 ) [TaxId: 11261 ],	SCOPe (2.08)

Chain	Domain	Class	Architecture	Topology	Provenance Source (Version)
A	1.20.5.300	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	CATH (4.3.0)
C	1.20.5.300	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	CATH (4.3.0)
E	1.20.5.300	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	CATH (4.3.0)
G	1.20.5.300	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	CATH (4.3.0)
I	1.20.5.300	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	CATH (4.3.0)
K	1.20.5.300	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	CATH (4.3.0)
M	1.20.5.300	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	CATH (4.3.0)
O	1.20.5.300	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	CATH (4.3.0)
Q	1.20.5.300	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	CATH (4.3.0)
S	1.20.5.300	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	CATH (4.3.0)
U	1.20.5.300	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	CATH (4.3.0)
W	1.20.5.300	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	CATH (4.3.0)
B	1.20.5.170	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	CATH (4.3.0)
L	1.20.5.170	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	CATH (4.3.0)

Chain

Domain

Class

Architecture

Topology

Homology

Provenance Source (Version)

1.20.5.300

Mainly Alpha

Up-down Bundle

Single alpha-helices involved in coiled-coils or other helix-helix interfaces

CATH (4.3.0)

1.20.5.300

Mainly Alpha

Up-down Bundle

Single alpha-helices involved in coiled-coils or other helix-helix interfaces

CATH (4.3.0)

1.20.5.300

Mainly Alpha

Up-down Bundle

Single alpha-helices involved in coiled-coils or other helix-helix interfaces

CATH (4.3.0)

1.20.5.300

Mainly Alpha

Up-down Bundle

Single alpha-helices involved in coiled-coils or other helix-helix interfaces

CATH (4.3.0)

1.20.5.300

Mainly Alpha

Up-down Bundle

Single alpha-helices involved in coiled-coils or other helix-helix interfaces

CATH (4.3.0)

1.20.5.300

Mainly Alpha

Up-down Bundle

Single alpha-helices involved in coiled-coils or other helix-helix interfaces

CATH (4.3.0)

1.20.5.300

Mainly Alpha

Up-down Bundle

Single alpha-helices involved in coiled-coils or other helix-helix interfaces

CATH (4.3.0)

1.20.5.300

Mainly Alpha

Up-down Bundle

Single alpha-helices involved in coiled-coils or other helix-helix interfaces

CATH (4.3.0)

1.20.5.300

Mainly Alpha

Up-down Bundle

Single alpha-helices involved in coiled-coils or other helix-helix interfaces

CATH (4.3.0)

1.20.5.300

Mainly Alpha

Up-down Bundle

Single alpha-helices involved in coiled-coils or other helix-helix interfaces

CATH (4.3.0)

1.20.5.300

Mainly Alpha

Up-down Bundle

Single alpha-helices involved in coiled-coils or other helix-helix interfaces

CATH (4.3.0)

1.20.5.300

Mainly Alpha

Up-down Bundle

Single alpha-helices involved in coiled-coils or other helix-helix interfaces

CATH (4.3.0)

1.20.5.170

Mainly Alpha

Up-down Bundle

Single alpha-helices involved in coiled-coils or other helix-helix interfaces

CATH (4.3.0)

1.20.5.170

Mainly Alpha

Up-down Bundle

Single alpha-helices involved in coiled-coils or other helix-helix interfaces

CATH (4.3.0)

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, C, E, G, I A, C, E, G, I, K, M, O, Q, S, U, W	FUSION PROTEIN (F)	-	membrane organization cellular component organization membrane fusion fusion of virus membrane with host plasma membrane viral process cellular process cellular component organization or biogenesis membrane fusion involved in viral entry into host cell virion attachment to host cell biological process involved in interspecies interaction between organisms receptor-mediated virion attachment to host cell adhesion of symbiont to host cell entry receptor-mediated virion attachment to host cell viral life cycle membrane organization cellular component organization membrane fusion fusion of virus membrane with host plasma membrane viral process cellular process cellular component organization or biogenesis membrane fusion involved in viral entry into host cell virion attachment to host cell biological process involved in interspecies interaction between organisms receptor-mediated virion attachment to host cell adhesion of symbiont to host cell entry receptor-mediated virion attachment to host cell viral life cycle adhesion of symbiont to host biological process involved in interaction with host biological process involved in symbiotic interaction symbiont entry into host cell symbiont entry into host positive regulation of cellular component organization regulation of cellular process regulation of cellular component organization regulation of syncytium formation by plasma membrane fusion regulation of developmental process positive regulation of biological process cell-cell fusion modulation by virus of host process modulation by virus of syncytium formation via plasma membrane fusion positive regulation of developmental process symbiont-mediated perturbation of host process anatomical structure development positive regulation of syncytium formation by virus syncytium formation induction by virus of host cell-cell fusion modulation of process of another organism positive regulation of cellular process modulation by virus of host cellular process developmental process regulation of biological process biological regulation positive regulation of syncytium formation by plasma membrane fusion syncytium formation by plasma membrane fusion anatomical structure morphogenesis anatomical structure formation involved in morphogenesis	virion component viral membrane viral envelope membrane cellular anatomical entity host cell plasma membrane host cellular component host cell part host cell membrane virion membrane host intracellular part host cell Golgi membrane host cell Golgi apparatus host cell cytoplasm part virion component viral membrane viral envelope membrane cellular anatomical entity host cell plasma membrane host cellular component host cell part host cell membrane virion membrane host intracellular part host cell Golgi membrane host cell Golgi apparatus host cell cytoplasm part host cell cytoplasm host cell endomembrane system host intracellular region
B, D, F, H, J B, D, F, H, J, L, N, P, R, T, V, X	FUSION PROTEIN (F)	-	membrane organization cellular component organization membrane fusion fusion of virus membrane with host plasma membrane viral process cellular process cellular component organization or biogenesis membrane fusion involved in viral entry into host cell virion attachment to host cell biological process involved in interspecies interaction between organisms receptor-mediated virion attachment to host cell adhesion of symbiont to host cell entry receptor-mediated virion attachment to host cell viral life cycle membrane organization cellular component organization membrane fusion fusion of virus membrane with host plasma membrane viral process cellular process cellular component organization or biogenesis membrane fusion involved in viral entry into host cell virion attachment to host cell biological process involved in interspecies interaction between organisms receptor-mediated virion attachment to host cell adhesion of symbiont to host cell entry receptor-mediated virion attachment to host cell viral life cycle adhesion of symbiont to host biological process involved in interaction with host biological process involved in symbiotic interaction symbiont entry into host cell symbiont entry into host positive regulation of cellular component organization regulation of cellular process regulation of cellular component organization regulation of syncytium formation by plasma membrane fusion regulation of developmental process positive regulation of biological process cell-cell fusion modulation by virus of host process modulation by virus of syncytium formation via plasma membrane fusion positive regulation of developmental process symbiont-mediated perturbation of host process anatomical structure development positive regulation of syncytium formation by virus syncytium formation induction by virus of host cell-cell fusion modulation of process of another organism positive regulation of cellular process modulation by virus of host cellular process developmental process regulation of biological process biological regulation positive regulation of syncytium formation by plasma membrane fusion syncytium formation by plasma membrane fusion anatomical structure morphogenesis anatomical structure formation involved in morphogenesis	virion component viral membrane viral envelope membrane cellular anatomical entity host cell plasma membrane host cellular component host cell part host cell membrane virion membrane host intracellular part host cell Golgi membrane host cell Golgi apparatus host cell cytoplasm part virion component viral membrane viral envelope membrane cellular anatomical entity host cell plasma membrane host cellular component host cell part host cell membrane virion membrane host intracellular part host cell Golgi membrane host cell Golgi apparatus host cell cytoplasm part host cell cytoplasm host cell endomembrane system host intracellular region

Chains

Polymer

Molecular Function

Biological Process

Cellular Component

A, C, E, G, I

FUSION PROTEIN (F)

membrane organization

cellular component organization

membrane fusion

fusion of virus membrane with host plasma membrane

viral process

cellular process

cellular component organization or biogenesis

membrane fusion involved in viral entry into host cell

virion attachment to host cell

biological process involved in interspecies interaction between organisms

receptor-mediated virion attachment to host cell

adhesion of symbiont to host cell

entry receptor-mediated virion attachment to host cell

cellular anatomical entity

host cell plasma membrane

host cellular component

host cell part

host cell membrane

virion membrane

host intracellular part

host cell Golgi membrane

host cell Golgi apparatus

host cell cytoplasm part

B, D, F, H, J

FUSION PROTEIN (F)

membrane organization

cellular component organization

membrane fusion

fusion of virus membrane with host plasma membrane

viral process

cellular process

cellular component organization or biogenesis

membrane fusion involved in viral entry into host cell

virion attachment to host cell

biological process involved in interspecies interaction between organisms

receptor-mediated virion attachment to host cell

adhesion of symbiont to host cell

entry receptor-mediated virion attachment to host cell

cellular anatomical entity

host cell plasma membrane

host cellular component

host cell part

host cell membrane

virion membrane

host intracellular part

host cell Golgi membrane

host cell Golgi apparatus

host cell cytoplasm part

Chains	Accession	Name	Type
A, C, E, G, I A, C, E, G, I, K, M, O, Q, S, U, W	IPR000776	Precursor fusion glycoprotein F0, Paramyxoviridae	Family
B, D, F, H, J B, D, F, H, J, L, N, P, R, T, V, X	IPR000776	Precursor fusion glycoprotein F0, Paramyxoviridae	Family

Chains

Accession

Name

Type

A, C, E, G, I