1G58

CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE GOLD DERIVATIVE

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1g58a_	Alpha and beta proteins (a+b)	YrdC/RibB	YrdC/RibB	3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB	3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
B	d1g58b_	Alpha and beta proteins (a+b)	YrdC/RibB	YrdC/RibB	3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB	3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	YrdC/RibB-like	8004472	3000166	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	YrdC/RibB-like	8004472	3000166	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	DHBP_synthase	e1g58A1	A: a+b complex topology	X: YrdC/RibB (From Topology)	H: YrdC/RibB (From Topology)	T: YrdC/RibB	F: DHBP_synthase	ECOD (1.6)
B	DHBP_synthase	e1g58B1	A: a+b complex topology	X: YrdC/RibB (From Topology)	H: YrdC/RibB (From Topology)	T: YrdC/RibB	F: DHBP_synthase	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.90.870.10	Alpha Beta	Alpha-Beta Complex	DHBP synthase	DHBP synthase	CATH (4.3.0)
B	3.90.870.10	Alpha Beta	Alpha-Beta Complex	DHBP synthase	DHBP synthase	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF00926	3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP_synthase)	3,4-dihydroxy-2-butanone 4-phosphate synthase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding manganese ion binding transition metal ion binding identical protein binding protein binding protein homodimerization activity protein dimerization activity lyase activity catalytic activity cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding manganese ion binding transition metal ion binding identical protein binding protein binding protein homodimerization activity protein dimerization activity lyase activity catalytic activity 3,4-dihydroxy-2-butanone-4-phosphate synthase activity carbon-carbon lyase activity	water-soluble vitamin biosynthetic process small molecule biosynthetic process cellular biosynthetic process flavin-containing compound metabolic process cellular metabolic process vitamin biosynthetic process riboflavin biosynthetic process vitamin metabolic process flavin-containing compound biosynthetic process biosynthetic process metabolic process small molecule metabolic process cellular process water-soluble vitamin metabolic process water-soluble vitamin biosynthetic process small molecule biosynthetic process cellular biosynthetic process flavin-containing compound metabolic process cellular metabolic process vitamin biosynthetic process riboflavin biosynthetic process vitamin metabolic process flavin-containing compound biosynthetic process biosynthetic process metabolic process small molecule metabolic process cellular process water-soluble vitamin metabolic process riboflavin metabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol cell periphery plasma membrane membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR017945	DHBP synthase RibB-like alpha/beta domain superfamily	Homologous Superfamily
A, B	IPR000422	3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.