1IYB

Crystal Structure of the Nicotiana glutinosa Ribonuclease NW

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1iyba1	Alpha and beta proteins (a+b)	Ribonuclease Rh-like	Ribonuclease Rh-like	Ribonuclease Rh-like	RNase NW	(Nicotiana glutinosa ) [TaxId: 35889 ],	SCOPe (2.08)
A	d1iyba2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Nicotiana glutinosa ) [TaxId: 35889 ],	SCOPe (2.08)
B	d1iybb1	Alpha and beta proteins (a+b)	Ribonuclease Rh-like	Ribonuclease Rh-like	Ribonuclease Rh-like	RNase NW	(Nicotiana glutinosa ) [TaxId: 35889 ],	SCOPe (2.08)
B	d1iybb2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Nicotiana glutinosa ) [TaxId: 35889 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Ribonuclease Rh-like	8023574	4001977	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Ribonuclease Rh-like	8035954	3000632	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	Ribonuclease Rh-like	8035954	3000632	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Ribonuclease_T2	e1iybA1	A: a+b two layers	X: Ribonuclease Rh-like (From Topology)	H: Ribonuclease Rh-like (From Topology)	T: Ribonuclease Rh-like	F: Ribonuclease_T2	ECOD (1.6)
B	Ribonuclease_T2	e1iybB1	A: a+b two layers	X: Ribonuclease Rh-like (From Topology)	H: Ribonuclease Rh-like (From Topology)	T: Ribonuclease Rh-like	F: Ribonuclease_T2	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.90.730.10	Alpha Beta	Alpha-Beta Complex	Ribonuclease Rh	Chain A	CATH (4.3.0)
B	3.90.730.10	Alpha Beta	Alpha-Beta Complex	Ribonuclease Rh	Chain A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF00445	Ribonuclease T2 family (Ribonuclease_T2)	Ribonuclease T2 family	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Ribonuclease	endonuclease activity catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA nuclease activity hydrolase activity phosphorus-oxygen lyase activity nuclease activity hydrolase activity, acting on ester bonds RNA endonuclease activity lyase activity catalytic activity ribonuclease T2 activity RNA binding binding endonuclease activity catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA nuclease activity hydrolase activity phosphorus-oxygen lyase activity nuclease activity hydrolase activity, acting on ester bonds RNA endonuclease activity lyase activity catalytic activity ribonuclease T2 activity RNA binding binding organic cyclic compound binding nucleic acid binding	catabolic process RNA metabolic process primary metabolic process nucleic acid metabolic process macromolecule catabolic process nucleobase-containing compound catabolic process nucleobase-containing compound metabolic process nucleic acid catabolic process metabolic process macromolecule metabolic process RNA catabolic process	extracellular region cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR018188	Ribonuclease T2, His active site 1	Active Site
A, B	IPR001568	Ribonuclease T2-like	Family
A, B	IPR033697	Ribonuclease T2, eukaryotic	Family
A, B	IPR036430	Ribonuclease T2-like superfamily	Homologous Superfamily
A, B	IPR033130	Ribonuclease T2, His active site 2	Active Site

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.