1JKP

Testing the Water-Mediated HIN Recombinase DNA Recognition by Systematic Mutations

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
C	d1jkpc_	All alpha proteins	DNA/RNA-binding 3-helical bundle	Homeodomain-like	Recombinase DNA-binding domain	HIN recombinase (DNA-binding domain)	( ) [TaxId: ], (Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) ) [TaxId: 99287 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
C	SCOP2B Superfamily	Homeodomain-like	8002428	3000001	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
C	HTH_7	e1jkpC1	A: alpha arrays	X: HTH	H: HTH	T: tri-helical	F: HTH_7	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
C	1.10.10.60	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Homeodomain-like	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
C	PF02796	Helix-turn-helix domain of resolvase (HTH_7)	Helix-turn-helix domain of resolvase	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	5'-D(TPGPTPTPTPTPTPGPAPGPAPAPGPA)-3'	-	-	-
B	5'-D(APTPCPTPTPCPTPCPAPAPAPAPAPC)-3'	-	-	-
C	DNA-INVERTASE HIN	DNA binding binding organic cyclic compound binding nucleic acid binding catalytic activity, acting on DNA catalytic activity, acting on a nucleic acid DNA strand exchange activity catalytic activity	nucleobase-containing compound metabolic process metabolic process primary metabolic process DNA metabolic process macromolecule metabolic process DNA integration nucleic acid metabolic process DNA recombination	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
C	IPR009057	Homedomain-like superfamily	Homologous Superfamily
C	IPR036162	Resolvase-like, N-terminal catalytic domain superfamily	Homologous Superfamily
C	IPR006118	Recombinase, conserved site	Conserved Site
C	IPR006119	Resolvase, N-terminal catalytic domain	Domain
C	IPR006120	Resolvase, HTH domain	Domain
C	IPR050639	Site-specific recombinase resolvase	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.