Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad1neka1 All alpha proteins Spectrin repeat-like Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain Succinate dehydogenase (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Ad1neka2 Alpha and beta proteins (a/b) FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain Succinate dehydogenase (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Ad1neka3 Alpha and beta proteins (a+b) Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydogenase (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Bd1nekb1 All alpha proteins Globin-like alpha-helical ferredoxin Fumarate reductase/Succinate dehydogenase iron-sulfur protein, C-terminal domain Succinate dehydogenase (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Bd1nekb2 Alpha and beta proteins (a+b) beta-Grasp (ubiquitin-like) 2Fe-2S ferredoxin-like 2Fe-2S ferredoxin domains from multidomain proteins Succinate dehydogenase iron-sulfur protein, N-terminal domain (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Cd1nekc_ Membrane and cell surface proteins and peptides Heme-binding four-helical bundle Fumarate reductase respiratory complex transmembrane subunits Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD) Succinate dehydrogenase subunit SdhC (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Dd1nekd_ Membrane and cell surface proteins and peptides Heme-binding four-helical bundle Fumarate reductase respiratory complex transmembrane subunits Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD) Succinate dehydrogenase subunit SdhD (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2 FamilyL-aspartate oxidase-like 8056066 4000053 SCOP2 (2022-06-29)
ASCOP2 SuperfamilySuccinate dehydrogenase/fumarate reductase domain-like 8056067 3000054 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyL-aspartate oxidase C-terminal domain-like 8056068 3000021 SCOP2 (2022-06-29)
BSCOP2 FamilyFumarate reductase/Succinate dehydogenase iron-sulfur protein, C-terminal domain-like 8003627 4000221 SCOP2 (2022-06-29)
BSCOP2 Family2Fe-2S ferredoxin domains from multidomain proteins 8003628 4000241 SCOP2 (2022-06-29)
BSCOP2 Superfamilyalpha-helical ferredoxin 8017662 3000026 SCOP2 (2022-06-29)
BSCOP2 Superfamily2Fe-2S ferredoxin-like 8017659 3000113 SCOP2 (2022-06-29)
CSCOP2 FamilySuccinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD) 8031387 4001916 SCOP2 (2022-06-29)
CSCOP2 SuperfamilyFumarate reductase respiratory complex transmembrane subunits 8043765 3000518 SCOP2 (2022-06-29)
DSCOP2 FamilySuccinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD) 8031390 4001916 SCOP2 (2022-06-29)
DSCOP2 SuperfamilyFumarate reductase respiratory complex transmembrane subunits 8043768 3000518 SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ASucc_DH_flav_Ce1nekA1 A: alpha bundlesX: Spectrin repeat-likeH: Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain (From Topology)T: Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domainF: Succ_DH_flav_CECOD (1.6)
AFAD_binding_2e1nekA2 A: a+b complex topologyX: Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain (From Topology)H: Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain (From Topology)T: Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domainF: FAD_binding_2ECOD (1.6)
AFAD_binding_3_1ste1nekA3 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: FAD_binding_3_1stECOD (1.6)
BFer4_8e1nekB1 A: alpha arraysX: alpha-helical ferredoxin-likeH: alpha-helical ferredoxin (From Topology)T: alpha-helical ferredoxinF: Fer4_8ECOD (1.6)
BFer2_3e1nekB2 A: a+b two layersX: beta-GraspH: Ubiquitin-relatedT: Ubiquitin-likeF: Fer2_3ECOD (1.6)
CSdh_cyte1nekC1 A: alpha bundlesX: Transmembrane heme-binding four-helical bundle (From Homology)H: Transmembrane heme-binding four-helical bundleT: Fumarate reductase respiratory complex transmembrane subunitsF: Sdh_cytECOD (1.6)
DSdh_cyte1nekD1 A: alpha bundlesX: Transmembrane heme-binding four-helical bundle (From Homology)H: Transmembrane heme-binding four-helical bundleT: Fumarate reductase respiratory complex transmembrane subunitsF: Sdh_cytECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF02910Fumarate reductase flavoprotein C-term (Succ_DH_flav_C)Fumarate reductase flavoprotein C-termThis family contains fumarate reductases, succinate dehydrogenases and L-aspartate oxidases.Domain
PF00890FAD binding domain (FAD_binding_2)FAD binding domain- Family
PF130852Fe-2S iron-sulfur cluster binding domain (Fer2_3)2Fe-2S iron-sulfur cluster binding domainThe 2Fe-2S ferredoxin family have a general core structure consisting of beta(2)-alpha-beta(2) which abeta-grasp type fold. The domain is around one hundred amino acids with four conserved cysteine residues to which the 2Fe-2S cluster is ligated.Domain
PF135344Fe-4S dicluster domain (Fer4_17)4Fe-4S dicluster domainThis family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.Domain
PF01127Succinate dehydrogenase/Fumarate reductase transmembrane subunit (Sdh_cyt)Succinate dehydrogenase/Fumarate reductase transmembrane subunit- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
Succinate dehydrogenase flavoprotein subunit
Succinate dehydrogenase iron-sulfur protein
Succinate dehydrogenase cytochrome b-556 subunit
Succinate dehydrogenase hydrophobic membrane anchor protein

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
IPR015939Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminalDomain
IPR003952Fumarate reductase/succinate dehydrogenase, FAD-binding siteBinding Site
IPR037099Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamilyHomologous Superfamily
IPR036188FAD/NAD(P)-binding domain superfamilyHomologous Superfamily
IPR003953FAD-dependent oxidoreductase 2, FAD binding domainDomain
IPR030664FAD-dependent oxidoreductase SdhA/FrdA/AprAFamily
IPR027477Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamilyHomologous Superfamily
IPR014006Succinate dehydrogenase/fumarate reductase, flavoprotein subunitFamily
IPR011281Succinate dehydrogenase, flavoprotein subunitFamily
IPR025192Succinate dehydogenase/fumarate reductase N-terminalDomain
IPR0360102Fe-2S ferredoxin-like superfamilyHomologous Superfamily
IPR0010412Fe-2S ferredoxin-type iron-sulfur binding domainDomain
IPR004489Succinate dehydrogenase/fumarate reductase iron-sulphur proteinFamily
IPR009051Alpha-helical ferredoxinHomologous Superfamily
IPR050573Succinate Dehydrogenase/Fumarate Reductase Iron-SulfurFamily
IPR0179004Fe-4S ferredoxin, iron-sulphur binding, conserved siteConserved Site
IPR0178964Fe-4S ferredoxin-type, iron-sulphur binding domainDomain
IPR012675Beta-grasp domain superfamilyHomologous Superfamily
IPR034804Fumarate reductase/succinate dehydrogenase, transmembrane subunitHomologous Superfamily
IPR014314Succinate dehydrogenase, cytochrome b556 subunitFamily
IPR018495Succinate dehydrogenase, cytochrome b subunit, conserved siteConserved Site
IPR000701Succinate dehydrogenase/fumarate reductase type B, transmembrane subunitFamily
IPR034804Fumarate reductase/succinate dehydrogenase, transmembrane subunitHomologous Superfamily
IPR000701Succinate dehydrogenase/fumarate reductase type B, transmembrane subunitFamily
IPR014312Succinate dehydrogenase, hydrophobic membrane anchorFamily

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

ChainsExternal LinkComment
A, B, C, D
PDBTMAnnotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage