Annotations: 1NOB

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1noba_	All beta proteins	Virus attachment protein globular domain	Virus attachment protein globular domain	Adenovirus fiber protein 'knob' domain	Adenovirus fiber protein 'knob' domain	(Human adenovirus 12 ) [TaxId: 28282 ],	SCOPe (2.08)
B	d1nobb_	All beta proteins	Virus attachment protein globular domain	Virus attachment protein globular domain	Adenovirus fiber protein 'knob' domain	Adenovirus fiber protein 'knob' domain	(Human adenovirus 12 ) [TaxId: 28282 ],	SCOPe (2.08)
C	d1nobc_	All beta proteins	Virus attachment protein globular domain	Virus attachment protein globular domain	Adenovirus fiber protein 'knob' domain	Adenovirus fiber protein 'knob' domain	(Human adenovirus 12 ) [TaxId: 28282 ],	SCOPe (2.08)
D	d1nobd_	All beta proteins	Virus attachment protein globular domain	Virus attachment protein globular domain	Adenovirus fiber protein 'knob' domain	Adenovirus fiber protein 'knob' domain	(Human adenovirus 12 ) [TaxId: 28282 ],	SCOPe (2.08)
E	d1nobe_	All beta proteins	Virus attachment protein globular domain	Virus attachment protein globular domain	Adenovirus fiber protein 'knob' domain	Adenovirus fiber protein 'knob' domain	(Human adenovirus 12 ) [TaxId: 28282 ],	SCOPe (2.08)
F	d1nobf_	All beta proteins	Virus attachment protein globular domain	Virus attachment protein globular domain	Adenovirus fiber protein 'knob' domain	Adenovirus fiber protein 'knob' domain	(Human adenovirus 12 ) [TaxId: 28282 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Virus attachment protein globular domain	8041213	3001376	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Virus attachment protein globular domain	8041213	3001376	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Virus attachment protein globular domain	8041213	3001376	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Virus attachment protein globular domain	8041213	3001376	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Virus attachment protein globular domain	8041213	3001376	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Virus attachment protein globular domain	8041213	3001376	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Adeno_knob	e1nobA1	A: beta sandwiches	X: Domain in virus attachment proteins (From Topology)	H: Domain in virus attachment proteins (From Topology)	T: Domain in virus attachment proteins	F: Adeno_knob	ECOD (1.6)
B	Adeno_knob	e1nobB1	A: beta sandwiches	X: Domain in virus attachment proteins (From Topology)	H: Domain in virus attachment proteins (From Topology)	T: Domain in virus attachment proteins	F: Adeno_knob	ECOD (1.6)
C	Adeno_knob	e1nobC1	A: beta sandwiches	X: Domain in virus attachment proteins (From Topology)	H: Domain in virus attachment proteins (From Topology)	T: Domain in virus attachment proteins	F: Adeno_knob	ECOD (1.6)
D	Adeno_knob	e1nobD1	A: beta sandwiches	X: Domain in virus attachment proteins (From Topology)	H: Domain in virus attachment proteins (From Topology)	T: Domain in virus attachment proteins	F: Adeno_knob	ECOD (1.6)
E	Adeno_knob	e1nobE1	A: beta sandwiches	X: Domain in virus attachment proteins (From Topology)	H: Domain in virus attachment proteins (From Topology)	T: Domain in virus attachment proteins	F: Adeno_knob	ECOD (1.6)
F	Adeno_knob	e1nobF1	A: beta sandwiches	X: Domain in virus attachment proteins (From Topology)	H: Domain in virus attachment proteins (From Topology)	T: Domain in virus attachment proteins	F: Adeno_knob	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.60.90.10	Mainly Beta	Sandwich	Adenovirus Type 5 Fiber Protein (Receptor Binding Domain)	Adenovirus pIV-related, attachment domain	CATH (4.3.0)
B	2.60.90.10	Mainly Beta	Sandwich	Adenovirus Type 5 Fiber Protein (Receptor Binding Domain)	Adenovirus pIV-related, attachment domain	CATH (4.3.0)
C	2.60.90.10	Mainly Beta	Sandwich	Adenovirus Type 5 Fiber Protein (Receptor Binding Domain)	Adenovirus pIV-related, attachment domain	CATH (4.3.0)
D	2.60.90.10	Mainly Beta	Sandwich	Adenovirus Type 5 Fiber Protein (Receptor Binding Domain)	Adenovirus pIV-related, attachment domain	CATH (4.3.0)
E	2.60.90.10	Mainly Beta	Sandwich	Adenovirus Type 5 Fiber Protein (Receptor Binding Domain)	Adenovirus pIV-related, attachment domain	CATH (4.3.0)
F	2.60.90.10	Mainly Beta	Sandwich	Adenovirus Type 5 Fiber Protein (Receptor Binding Domain)	Adenovirus pIV-related, attachment domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F	PF00541	Adenoviral fibre protein (knob domain) (Adeno_knob)	Adenoviral fibre protein (knob domain)	Specific attachment of adenovirus is achieved through interactions between host-cell receptors and the adenovirus fibre protein and is mediated by the globular carboxy-terminal domain of the adenovirus fibre protein, termed the carboxy-terminal kn ...	Specific attachment of adenovirus is achieved through interactions between host-cell receptors and the adenovirus fibre protein and is mediated by the globular carboxy-terminal domain of the adenovirus fibre protein, termed the carboxy-terminal knob domain.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F	PROTEIN (FIBER KNOB PROTEIN)	-	virion attachment to host cell biological process involved in interspecies interaction between organisms receptor-mediated virion attachment to host cell adhesion of symbiont to host cell viral process viral life cycle adhesion of symbiont to host adhesion receptor-mediated virion attachment to host cell biological process involved in interaction with host biological process involved in symbiotic interaction cell adhesion cellular process symbiont entry into host cell symbiont entry into host	viral capsid virion component host intracellular membrane-bounded organelle host cellular component host intracellular part host cell part host intracellular region cellular anatomical entity host cell nucleus host intracellular organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F	IPR009013	Attachment protein shaft domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F	IPR000978	Adenoviral fibre protein, knob	Domain
A, B, C, D, E A, B, C, D, E, F	IPR008982	Adenovirus pIV-like, attachment domain	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F	IPR000931	Adenovirus fibre protein	Family
A, B, C, D, E A, B, C, D, E, F	IPR000939	Adenoviral fibre protein, repeat/shaft region	Repeat

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.