1NSK
THE CRYSTAL STRUCTURE OF A HUMAN NUCLEOSIDE DIPHOSPHATE KINASE, NM23-H2
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A [auth R] | SCOP2B Superfamily | Nucleoside diphosphate kinase, NDK | 8038962 | 3001175 | SCOP2B (2022-06-29) |
B [auth L] | SCOP2B Superfamily | Nucleoside diphosphate kinase, NDK | 8038962 | 3001175 | SCOP2B (2022-06-29) |
C [auth T] | SCOP2B Superfamily | Nucleoside diphosphate kinase, NDK | 8038962 | 3001175 | SCOP2B (2022-06-29) |
D [auth U] | SCOP2B Superfamily | Nucleoside diphosphate kinase, NDK | 8038962 | 3001175 | SCOP2B (2022-06-29) |
E [auth N] | SCOP2B Superfamily | Nucleoside diphosphate kinase, NDK | 8038962 | 3001175 | SCOP2B (2022-06-29) |
F [auth O] | SCOP2B Superfamily | Nucleoside diphosphate kinase, NDK | 8038962 | 3001175 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A [auth R] | NDK | e1nskR1 | A: a+b two layers | X: Alpha-beta plaits | H: Nucleoside diphosphate kinases (From Topology) | T: Nucleoside diphosphate kinases | F: NDK | ECOD (1.6) |
B [auth L] | NDK | e1nskL1 | A: a+b two layers | X: Alpha-beta plaits | H: Nucleoside diphosphate kinases (From Topology) | T: Nucleoside diphosphate kinases | F: NDK | ECOD (1.6) |
C [auth T] | NDK | e1nskT1 | A: a+b two layers | X: Alpha-beta plaits | H: Nucleoside diphosphate kinases (From Topology) | T: Nucleoside diphosphate kinases | F: NDK | ECOD (1.6) |
D [auth U] | NDK | e1nskU1 | A: a+b two layers | X: Alpha-beta plaits | H: Nucleoside diphosphate kinases (From Topology) | T: Nucleoside diphosphate kinases | F: NDK | ECOD (1.6) |
E [auth N] | NDK | e1nskN1 | A: a+b two layers | X: Alpha-beta plaits | H: Nucleoside diphosphate kinases (From Topology) | T: Nucleoside diphosphate kinases | F: NDK | ECOD (1.6) |
F [auth O] | NDK | e1nskO1 | A: a+b two layers | X: Alpha-beta plaits | H: Nucleoside diphosphate kinases (From Topology) | T: Nucleoside diphosphate kinases | F: NDK | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A [auth R] | 3.30.70.141 | Alpha Beta | 2-Layer Sandwich | Alpha-Beta Plaits | Nucleoside diphosphate kinase-like domain | CATH (4.3.0) |
B [auth L] | 3.30.70.141 | Alpha Beta | 2-Layer Sandwich | Alpha-Beta Plaits | Nucleoside diphosphate kinase-like domain | CATH (4.3.0) |
C [auth T] | 3.30.70.141 | Alpha Beta | 2-Layer Sandwich | Alpha-Beta Plaits | Nucleoside diphosphate kinase-like domain | CATH (4.3.0) |
D [auth U] | 3.30.70.141 | Alpha Beta | 2-Layer Sandwich | Alpha-Beta Plaits | Nucleoside diphosphate kinase-like domain | CATH (4.3.0) |
E [auth N] | 3.30.70.141 | Alpha Beta | 2-Layer Sandwich | Alpha-Beta Plaits | Nucleoside diphosphate kinase-like domain | CATH (4.3.0) |
F [auth O] | 3.30.70.141 | Alpha Beta | 2-Layer Sandwich | Alpha-Beta Plaits | Nucleoside diphosphate kinase-like domain | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00334 | Nucleoside diphosphate kinase (NDK) | Nucleoside diphosphate kinase | - | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR023005 | Nucleoside diphosphate kinase, active site | Active Site | |
IPR034907 | Nucleoside diphosphate kinase-like domain | Domain | |
IPR036850 | Nucleoside diphosphate kinase-like domain superfamily | Homologous Superfamily | |
IPR001564 | Nucleoside diphosphate kinase | Family |
Pharos: Disease Associations Pharos Homepage Annotation
Chains | Drug Target   | Associated Disease |
---|---|---|
P22392 | :