Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2 FamilyeIF2alpha middle domain-like 8029769 4002794 SCOP2 (2022-06-29)
ASCOP2 FamilyCold shock DNA-binding domain-like 8029770 4001909 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyeIF2alpha middle domain-like 8042148 3001761 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyNucleic acid-binding proteins 8042149 3000135 SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AS1_1e1q46A1 A: beta barrelsX: OB-foldH: Nucleic acid-binding proteins (From Topology)T: Nucleic acid-binding proteinsF: S1_1ECOD (1.6)
AEIF_2_alpha_Ne1q46A2 A: alpha arraysX: HhH/H2THH: eIF2alpha middle domain (From Topology)T: eIF2alpha middle domainF: EIF_2_alpha_NECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A2.40.50.140 Mainly Beta Beta Barrel OB fold (Dihydrolipoamide Acetyltransferase, E2P) Nucleic acid-binding proteinsCATH (4.3.0)
A1.10.150.190 Mainly Alpha Orthogonal Bundle DNA polymerase domain 1CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF07541Eukaryotic translation initiation factor 2 alpha subunit (EIF_2_alpha)Eukaryotic translation initiation factor 2 alpha subunit- Family
PF00575S1 RNA binding domain (S1)S1 RNA binding domainThe S1 domain occurs in a wide range of RNA associated proteins. It is structurally similar to cold shock protein which binds nucleic acids. The S1 domain has an OB-fold structure.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
translation initiation factor 2 alpha subunit