1ST0
Structure of DcpS bound to m7GpppG
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A [auth B] | SCOP2B Superfamily | mRNA decapping enzyme DcpS N-terminal domain | 8041668 | 3001367 | SCOP2B (2022-06-29) |
A [auth B] | SCOP2B Superfamily | HIT-like | 8041667 | 3000223 | SCOP2B (2022-06-29) |
B [auth A] | SCOP2 Family | DcpS C-terminal domain-like | 8029288 | 4001251 | SCOP2 (2022-06-29) |
B [auth A] | SCOP2 Family | mRNA decapping enzyme DcpS N-terminal domain | 8029289 | 4001353 | SCOP2 (2022-06-29) |
B [auth A] | SCOP2 Superfamily | HIT-like | 8041667 | 3000223 | SCOP2 (2022-06-29) |
B [auth A] | SCOP2 Superfamily | mRNA decapping enzyme DcpS N-terminal domain | 8041668 | 3001367 | SCOP2 (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A [auth B] | DcpS | e1st0B1 | A: a+b two layers | X: mRNA decapping enzyme DcpS N-terminal domain (From Topology) | H: mRNA decapping enzyme DcpS N-terminal domain (From Topology) | T: mRNA decapping enzyme DcpS N-terminal domain | F: DcpS | ECOD (1.6) |
A [auth B] | DcpS_C | e1st0B2 | A: a+b three layers | X: HIT-like | H: HIT-related (From Topology) | T: HIT-related | F: DcpS_C | ECOD (1.6) |
B [auth A] | DcpS | e1st0A1 | A: a+b two layers | X: mRNA decapping enzyme DcpS N-terminal domain (From Topology) | H: mRNA decapping enzyme DcpS N-terminal domain (From Topology) | T: mRNA decapping enzyme DcpS N-terminal domain | F: DcpS | ECOD (1.6) |
B [auth A] | DcpS_C | e1st0A2 | A: a+b three layers | X: HIT-like | H: HIT-related (From Topology) | T: HIT-related | F: DcpS_C | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A [auth B] | 3.30.200.40 | Alpha Beta | 2-Layer Sandwich | Phosphorylase Kinase | domain 1 | CATH (4.3.0) |
A [auth B] | 3.30.2240.10 | Alpha Beta | 2-Layer Sandwich | mRNA decapping enzyme DcpS N-terminal fold | mRNA decapping enzyme DcpS N-terminal domain | CATH (4.3.0) |
A [auth B] | 3.30.428.10 | Alpha Beta | 2-Layer Sandwich | HIT family, subunit A | HIT-like | CATH (4.3.0) |
B [auth A] | 3.30.200.40 | Alpha Beta | 2-Layer Sandwich | Phosphorylase Kinase | domain 1 | CATH (4.3.0) |
B [auth A] | 3.30.428.10 | Alpha Beta | 2-Layer Sandwich | HIT family, subunit A | HIT-like | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
A [auth B], B [auth A] | PF11969 | Scavenger mRNA decapping enzyme C-term binding (DcpS_C) | Scavenger mRNA decapping enzyme C-term binding | - | Family |
A [auth B], B [auth A] | PF05652 | Scavenger mRNA decapping enzyme (DcpS) N-terminal (DcpS) | Scavenger mRNA decapping enzyme (DcpS) N-terminal | - | Family |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
A [auth B], B [auth A] | IPR011145 | Scavenger mRNA decapping enzyme, N-terminal | Homologous Superfamily |
A [auth B], B [auth A] | IPR008594 | Scavenger mRNA decapping enzyme DcpS/DCS2 | Family |
A [auth B], B [auth A] | IPR036265 | HIT-like superfamily | Homologous Superfamily |
A [auth B], B [auth A] | IPR019808 | Histidine triad, conserved site | Conserved Site |
Pharos: Disease Associations Pharos Homepage Annotation
Chains | Drug Target   | Associated Disease |
---|---|---|
A [auth B], B [auth A] | Q96C86 | :