1W1H
Crystal Structure of the PDK1 Pleckstrin Homology (PH) domain
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d1w1ha_ | All beta proteins | PH domain-like barrel | PH domain-like | Pleckstrin-homology domain (PH domain) | 3-phosphoinositide dependent protein kinase-1 | HUMAN (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
B | d1w1hb1 | All beta proteins | PH domain-like barrel | PH domain-like | Pleckstrin-homology domain (PH domain) | 3-phosphoinositide dependent protein kinase-1 | HUMAN (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
B | d1w1hb2 | Artifacts | Tags | Tags | Tags | N-terminal Tags | HUMAN (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
C | d1w1hc_ | All beta proteins | PH domain-like barrel | PH domain-like | Pleckstrin-homology domain (PH domain) | 3-phosphoinositide dependent protein kinase-1 | HUMAN (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
D | d1w1hd_ | All beta proteins | PH domain-like barrel | PH domain-like | Pleckstrin-homology domain (PH domain) | 3-phosphoinositide dependent protein kinase-1 | HUMAN (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2 Family | Pleckstrin-homology domain (PH domain) | 8030834 | 4002395 | SCOP2 (2022-06-29) |
A | SCOP2 Superfamily | PH domain-like | 8043213 | 3000134 | SCOP2 (2022-06-29) |
B | SCOP2B Superfamily | PH domain-like | 8043213 | 3000134 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | PH domain-like | 8043213 | 3000134 | SCOP2B (2022-06-29) |
D | SCOP2B Superfamily | PH domain-like | 8043213 | 3000134 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | PH_3 | e1w1hA1 | A: beta barrels | X: PH domain-like | H: PH domain-like (From Topology) | T: PH domain-like | F: PH_3 | ECOD (1.6) |
B | PH_3 | e1w1hB1 | A: beta barrels | X: PH domain-like | H: PH domain-like (From Topology) | T: PH domain-like | F: PH_3 | ECOD (1.6) |
C | PH_3 | e1w1hC1 | A: beta barrels | X: PH domain-like | H: PH domain-like (From Topology) | T: PH domain-like | F: PH_3 | ECOD (1.6) |
D | PH_3 | e1w1hD1 | A: beta barrels | X: PH domain-like | H: PH domain-like (From Topology) | T: PH domain-like | F: PH_3 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 2.30.29.30 | Mainly Beta | Roll | PH-domain like | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | CATH (4.3.0) |
B | 2.30.29.30 | Mainly Beta | Roll | PH-domain like | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | CATH (4.3.0) |
C | 2.30.29.30 | Mainly Beta | Roll | PH-domain like | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | CATH (4.3.0) |
D | 2.30.29.30 | Mainly Beta | Roll | PH-domain like | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR039046 | PDPK1 family | Family | |
IPR000719 | Protein kinase domain | Domain | |
IPR033931 | PDK1-type, PH domain | Domain | |
IPR050236 | Serine/threonine-protein kinases, AGC | Family | |
IPR017441 | Protein kinase, ATP binding site | Binding Site | |
IPR011993 | PH-like domain superfamily | Homologous Superfamily | |
IPR011009 | Protein kinase-like domain superfamily | Homologous Superfamily | |
IPR008271 | Serine/threonine-protein kinase, active site | Active Site |