1Y23

Crystal structure of a member of HIT family of proteins from bacillus subtilis

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1y23a_	Alpha and beta proteins (a+b)	HIT-like	HIT-like	HIT (HINT, histidine triad) family of protein kinase-interacting proteins	Hit	(Bacillus subtilis ) [TaxId: 1423 ],	SCOPe (2.08)
B	d1y23b_	Alpha and beta proteins (a+b)	HIT-like	HIT-like	HIT (HINT, histidine triad) family of protein kinase-interacting proteins	Hit	(Bacillus subtilis ) [TaxId: 1423 ],	SCOPe (2.08)
C	d1y23c_	Alpha and beta proteins (a+b)	HIT-like	HIT-like	HIT (HINT, histidine triad) family of protein kinase-interacting proteins	Hit	(Bacillus subtilis ) [TaxId: 1423 ],	SCOPe (2.08)
D	d1y23d_	Alpha and beta proteins (a+b)	HIT-like	HIT-like	HIT (HINT, histidine triad) family of protein kinase-interacting proteins	Hit	(Bacillus subtilis ) [TaxId: 1423 ],	SCOPe (2.08)
E	d1y23e_	Alpha and beta proteins (a+b)	HIT-like	HIT-like	HIT (HINT, histidine triad) family of protein kinase-interacting proteins	Hit	(Bacillus subtilis ) [TaxId: 1423 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	HIT domain-like	8031895	4000950	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	HIT-like	8044273	3000223	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	HIT-like	8044273	3000223	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	HIT-like	8044273	3000223	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	HIT-like	8044273	3000223	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	HIT-like	8044273	3000223	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	HIT	e1y23A1	A: a+b three layers	X: HIT-like	H: HIT-related (From Topology)	T: HIT-related	F: HIT	ECOD (1.6)
B	HIT	e1y23B1	A: a+b three layers	X: HIT-like	H: HIT-related (From Topology)	T: HIT-related	F: HIT	ECOD (1.6)
C	HIT	e1y23C1	A: a+b three layers	X: HIT-like	H: HIT-related (From Topology)	T: HIT-related	F: HIT	ECOD (1.6)
D	HIT	e1y23D1	A: a+b three layers	X: HIT-like	H: HIT-related (From Topology)	T: HIT-related	F: HIT	ECOD (1.6)
E	HIT	e1y23E1	A: a+b three layers	X: HIT-like	H: HIT-related (From Topology)	T: HIT-related	F: HIT	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.428.10	Alpha Beta	2-Layer Sandwich	HIT family, subunit A	HIT-like	CATH (4.3.0)
B	3.30.428.10	Alpha Beta	2-Layer Sandwich	HIT family, subunit A	HIT-like	CATH (4.3.0)
B	1.20.5.1170	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	HIT-like	CATH (4.3.0)
C	3.30.428.10	Alpha Beta	2-Layer Sandwich	HIT family, subunit A	HIT-like	CATH (4.3.0)
C	1.20.5.1170	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	HIT-like	CATH (4.3.0)
D	3.30.428.10	Alpha Beta	2-Layer Sandwich	HIT family, subunit A	HIT-like	CATH (4.3.0)
D	1.20.5.1170	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	HIT-like	CATH (4.3.0)
E	3.30.428.10	Alpha Beta	2-Layer Sandwich	HIT family, subunit A	HIT-like	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E	PF01230	HIT domain (HIT)	HIT domain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E	Histidine triad protein	catalytic activity	nucleoside phosphate metabolic process cellular metabolic process primary metabolic process nucleotide metabolic process nucleobase-containing compound metabolic process organophosphate metabolic process nucleobase-containing small molecule metabolic process phosphate-containing compound metabolic process metabolic process cellular process small molecule metabolic process phosphorus metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E	IPR036265	HIT-like superfamily	Homologous Superfamily
A, B, C, D, E	IPR001310	Histidine triad (HIT) protein	Family
A, B, C, D, E	IPR039384	HINT family	Family
A, B, C, D, E	IPR011146	HIT-like domain	Domain
A, B, C, D, E	IPR019808	Histidine triad, conserved site	Conserved Site

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.