1YCK
Crystal structure of human peptidoglycan recognition protein (PGRP-S)
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d1ycka1 | Alpha and beta proteins (a+b) | N-acetylmuramoyl-L-alanine amidase-like | N-acetylmuramoyl-L-alanine amidase-like | N-acetylmuramoyl-L-alanine amidase-like | Peptidoglycan recognition protein, PGRP-S | human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | Amidase_2 | e1yckA1 | A: a+b three layers | X: N-acetylmuramoyl-L-alanine amidase-like (From Topology) | H: N-acetylmuramoyl-L-alanine amidase-like (From Topology) | T: N-acetylmuramoyl-L-alanine amidase-like | F: Amidase_2 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.40.80.10 | Alpha Beta | 3-Layer(aba) Sandwich | Lysozyme-like | Peptidoglycan recognition protein-like | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF01510 | N-acetylmuramoyl-L-alanine amidase (Amidase_2) | N-acetylmuramoyl-L-alanine amidase | This family includes zinc amidases that have N-acetylmuramoyl-L-alanine amidase activity EC:3.5.1.28. This enzyme domain cleaves the amide bond between N-acetylmuramoyl and L-amino acids in bacterial cell walls (preferentially: D-lactyl-L-Ala). The ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR017331 | Peptidoglycan recognition protein, PGRP-S | Family | |
IPR002502 | N-acetylmuramoyl-L-alanine amidase domain | Domain | |
IPR006619 | Peptidoglycan recognition protein family domain, metazoa/bacteria | Domain | |
IPR036505 | N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily | Homologous Superfamily | |
IPR015510 | Peptidoglycan recognition protein | Family |
Pharos: Disease Associations Pharos Homepage Annotation
Chains | Drug Target   | Associated Disease |
---|---|---|
O75594 | :