1NF6

X-ray structure of the Desulfovibrio desulfuricans bacterioferritin: the diiron site in different catalytic states ("cycled" structure: reduced in solution and allowed to reoxidise before crystallisation)

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1nf6a_	All alpha proteins	Ferritin-like	Ferritin-like	Ferritin	Bacterioferritin (cytochrome b1)	(Desulfovibrio desulfuricans ) [TaxId: 876 ],	SCOPe (2.08)
B	d1nf6b_	All alpha proteins	Ferritin-like	Ferritin-like	Ferritin	Bacterioferritin (cytochrome b1)	(Desulfovibrio desulfuricans ) [TaxId: 876 ],	SCOPe (2.08)
C	d1nf6c_	All alpha proteins	Ferritin-like	Ferritin-like	Ferritin	Bacterioferritin (cytochrome b1)	(Desulfovibrio desulfuricans ) [TaxId: 876 ],	SCOPe (2.08)
D	d1nf6d_	All alpha proteins	Ferritin-like	Ferritin-like	Ferritin	Bacterioferritin (cytochrome b1)	(Desulfovibrio desulfuricans ) [TaxId: 876 ],	SCOPe (2.08)
E	d1nf6e_	All alpha proteins	Ferritin-like	Ferritin-like	Ferritin	Bacterioferritin (cytochrome b1)	(Desulfovibrio desulfuricans ) [TaxId: 876 ],	SCOPe (2.08)
F	d1nf6f_	All alpha proteins	Ferritin-like	Ferritin-like	Ferritin	Bacterioferritin (cytochrome b1)	(Desulfovibrio desulfuricans ) [TaxId: 876 ],	SCOPe (2.08)
H	d1nf6h_	All alpha proteins	Ferritin-like	Ferritin-like	Ferritin	Bacterioferritin (cytochrome b1)	(Desulfovibrio desulfuricans ) [TaxId: 876 ],	SCOPe (2.08)
I	d1nf6i_	All alpha proteins	Ferritin-like	Ferritin-like	Ferritin	Bacterioferritin (cytochrome b1)	(Desulfovibrio desulfuricans ) [TaxId: 876 ],	SCOPe (2.08)
J	d1nf6j_	All alpha proteins	Ferritin-like	Ferritin-like	Ferritin	Bacterioferritin (cytochrome b1)	(Desulfovibrio desulfuricans ) [TaxId: 876 ],	SCOPe (2.08)
K	d1nf6k_	All alpha proteins	Ferritin-like	Ferritin-like	Ferritin	Bacterioferritin (cytochrome b1)	(Desulfovibrio desulfuricans ) [TaxId: 876 ],	SCOPe (2.08)
L	d1nf6l_	All alpha proteins	Ferritin-like	Ferritin-like	Ferritin	Bacterioferritin (cytochrome b1)	(Desulfovibrio desulfuricans ) [TaxId: 876 ],	SCOPe (2.08)
M	d1nf6m_	All alpha proteins	Ferritin-like	Ferritin-like	Ferritin	Bacterioferritin (cytochrome b1)	(Desulfovibrio desulfuricans ) [TaxId: 876 ],	SCOPe (2.08)
N	d1nf6n_	All alpha proteins	Ferritin-like	Ferritin-like	Ferritin	Bacterioferritin (cytochrome b1)	(Desulfovibrio desulfuricans ) [TaxId: 876 ],	SCOPe (2.08)
O	d1nf6o_	All alpha proteins	Ferritin-like	Ferritin-like	Ferritin	Bacterioferritin (cytochrome b1)	(Desulfovibrio desulfuricans ) [TaxId: 876 ],	SCOPe (2.08)
P	d1nf6p_	All alpha proteins	Ferritin-like	Ferritin-like	Ferritin	Bacterioferritin (cytochrome b1)	(Desulfovibrio desulfuricans ) [TaxId: 876 ],	SCOPe (2.08)
G	d1nf6g_	All alpha proteins	Ferritin-like	Ferritin-like	Ferritin	Bacterioferritin (cytochrome b1)	(Desulfovibrio desulfuricans ) [TaxId: 876 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Ferritin-like	8033263	3001658	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Ferritin-like	8033263	3001658	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Ferritin-like	8033263	3001658	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Ferritin-like	8033263	3001658	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Ferritin-like	8033263	3001658	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Ferritin-like	8033263	3001658	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Ferritin-like	8033263	3001658	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	Ferritin-like	8033263	3001658	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	Ferritin-like	8033263	3001658	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	Ferritin-like	8033263	3001658	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	Ferritin-like	8033263	3001658	SCOP2B (2022-06-29)
M	SCOP2B Superfamily	Ferritin-like	8033263	3001658	SCOP2B (2022-06-29)
N	SCOP2B Superfamily	Ferritin-like	8033263	3001658	SCOP2B (2022-06-29)
O	SCOP2B Superfamily	Ferritin-like	8033263	3001658	SCOP2B (2022-06-29)
P	SCOP2B Superfamily	Ferritin-like	8033263	3001658	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Ferritin-like	8033263	3001658	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Ferritin	e1nf6A1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
B	Ferritin	e1nf6B1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
C	Ferritin	e1nf6C1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
D	Ferritin	e1nf6D1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
E	Ferritin	e1nf6E1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
F	Ferritin	e1nf6F1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
H	Ferritin	e1nf6H1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
I	Ferritin	e1nf6I1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
J	Ferritin	e1nf6J1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
K	Ferritin	e1nf6K1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
L	Ferritin	e1nf6L1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
M	Ferritin	e1nf6M1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
N	Ferritin	e1nf6N1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
O	Ferritin	e1nf6O1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
P	Ferritin	e1nf6P1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
G	Ferritin	e1nf6G1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
B	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
C	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
D	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
E	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
F	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
H	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
I	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
J	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
K	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
L	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
M	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
N	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
O	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
P	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
G	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	PF00210	Ferritin-like domain (Ferritin)	Ferritin-like domain	This family contains ferritins and other ferritin-like proteins such as members of the DPS family and bacterioferritins.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	bacterioferritin	cation binding ferric iron binding transition metal ion binding iron ion binding ion binding binding metal ion binding small molecule binding organic cyclic compound binding tetrapyrrole binding heme binding oxidoreductase activity, acting on metal ions oxidoreductase activity ferroxidase activity cation binding ferric iron binding transition metal ion binding iron ion binding ion binding binding metal ion binding small molecule binding organic cyclic compound binding tetrapyrrole binding heme binding oxidoreductase activity, acting on metal ions oxidoreductase activity ferroxidase activity oxidoreductase activity, acting on metal ions, oxygen as acceptor catalytic activity	cellular localization inorganic ion homeostasis homeostatic process sequestering of metal ion maintenance of location in cell maintenance of location localization intracellular iron ion homeostasis cellular homeostasis chemical homeostasis sequestering of iron ion intracellular monoatomic cation homeostasis monoatomic ion homeostasis intracellular chemical homeostasis cellular localization inorganic ion homeostasis homeostatic process sequestering of metal ion maintenance of location in cell maintenance of location localization intracellular iron ion homeostasis cellular homeostasis chemical homeostasis sequestering of iron ion intracellular monoatomic cation homeostasis monoatomic ion homeostasis intracellular chemical homeostasis cellular process intracellular sequestering of iron ion monoatomic cation homeostasis intracellular monoatomic ion homeostasis transport iron ion transport transition metal ion transport monoatomic ion transport monoatomic cation transport establishment of localization metal ion transport	cellular anatomical structure intracellular anatomical structure cytoplasm cytosol

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	IPR009040	Ferritin-like diiron domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	IPR002024	Bacterioferritin	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	IPR012347	Ferritin-like	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	IPR009078	Ferritin-like superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	IPR008331	Ferritin/DPS protein domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.