1NW4

Crystal Structure of Plasmodium falciparum Purine Nucleoside Phosphorylase in complex with ImmH and Sulfate


Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyPurine and uridine phosphorylases 8039540 3000626 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyPurine and uridine phosphorylases 8039540 3000626 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyPurine and uridine phosphorylases 8039540 3000626 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyPurine and uridine phosphorylases 8039540 3000626 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyPurine and uridine phosphorylases 8039540 3000626 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyPurine and uridine phosphorylases 8039540 3000626 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APNP_UDP_1e1nw4A1 A: a/b three-layered sandwichesX: Phosphorylase/hydrolase-likeH: Peptidyl-tRNA hydrolase-like (From Topology)T: Peptidyl-tRNA hydrolase-likeF: PNP_UDP_1ECOD (1.6)
CPNP_UDP_1e1nw4C1 A: a/b three-layered sandwichesX: Phosphorylase/hydrolase-likeH: Peptidyl-tRNA hydrolase-like (From Topology)T: Peptidyl-tRNA hydrolase-likeF: PNP_UDP_1ECOD (1.6)
DPNP_UDP_1e1nw4D1 A: a/b three-layered sandwichesX: Phosphorylase/hydrolase-likeH: Peptidyl-tRNA hydrolase-like (From Topology)T: Peptidyl-tRNA hydrolase-likeF: PNP_UDP_1ECOD (1.6)
EPNP_UDP_1e1nw4E1 A: a/b three-layered sandwichesX: Phosphorylase/hydrolase-likeH: Peptidyl-tRNA hydrolase-like (From Topology)T: Peptidyl-tRNA hydrolase-likeF: PNP_UDP_1ECOD (1.6)
FPNP_UDP_1e1nw4F1 A: a/b three-layered sandwichesX: Phosphorylase/hydrolase-likeH: Peptidyl-tRNA hydrolase-like (From Topology)T: Peptidyl-tRNA hydrolase-likeF: PNP_UDP_1ECOD (1.6)
BPNP_UDP_1e1nw4B1 A: a/b three-layered sandwichesX: Phosphorylase/hydrolase-likeH: Peptidyl-tRNA hydrolase-like (From Topology)T: Peptidyl-tRNA hydrolase-likeF: PNP_UDP_1ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D, E
PF01048Phosphorylase superfamily (PNP_UDP_1)Phosphorylase superfamilyMembers of this family include: purine nucleoside phosphorylase (PNP) Uridine phosphorylase (UdRPase) 5'-methylthioadenosine phosphorylase (MTA phosphorylase)Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C, D, E
uridine phosphorylase, putative

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C, D, E
IPR035994Nucleoside phosphorylase superfamilyHomologous Superfamily
A, B, C, D, E
IPR000845Nucleoside phosphorylase domainDomain