Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad1q0qa1 All alpha proteins Left-handed superhelix 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Ad1q0qa2 Alpha and beta proteins (a/b) NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Ad1q0qa3 Alpha and beta proteins (a+b) FwdE/GAPDH domain-like Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Dihydrodipicolinate reductase-like 1-deoxy-D-xylulose-5-phosphate reductoisomerase (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Bd1q0qb1 All alpha proteins Left-handed superhelix 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Bd1q0qb2 Alpha and beta proteins (a/b) NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Bd1q0qb3 Alpha and beta proteins (a+b) FwdE/GAPDH domain-like Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Dihydrodipicolinate reductase-like 1-deoxy-D-xylulose-5-phosphate reductoisomerase (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2 FamilyDXP reductoisomerase-like 8000977 4000096 SCOP2 (2022-06-29)
ASCOP2 FamilyDXP reductoisomerase C-terminal domain-like 8091675 4007753 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyGAPDH-like 8000978 3000043 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyDXP reductoisomerase C-terminal domain-like 8056156 3000022 SCOP2 (2022-06-29)
BSCOP2B SuperfamilyDXP reductoisomerase C-terminal domain-like 8056156 3000022 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyGAPDH-like 8000978 3000043 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ADXPR_Ce1q0qA1 A: alpha superhelicesX: 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C (From Topology)H: 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C (From Topology)T: 1-deoxy-D-xylulose-5-phosphate reductoisomerase-CF: DXPR_CECOD (1.6)
ADXP_redisom_Ce1q0qA3 A: a+b two layersX: FwdE/GAPDH domain-likeH: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology)T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainF: DXP_redisom_CECOD (1.6)
ADXP_reductoisome1q0qA2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: DXP_reductoisomECOD (1.6)
BDXPR_Ce1q0qB1 A: alpha superhelicesX: 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C (From Topology)H: 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C (From Topology)T: 1-deoxy-D-xylulose-5-phosphate reductoisomerase-CF: DXPR_CECOD (1.6)
BDXP_redisom_Ce1q0qB2 A: a+b two layersX: FwdE/GAPDH domain-likeH: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology)T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainF: DXP_redisom_CECOD (1.6)
BDXP_reductoisome1q0qB3 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: DXP_reductoisomECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF026701-deoxy-D-xylulose 5-phosphate reductoisomerase (DXP_reductoisom)1-deoxy-D-xylulose 5-phosphate reductoisomerase- Family
A, B
PF13288DXP reductoisomerase C-terminal domain (DXPR_C)DXP reductoisomerase C-terminal domainThis is the C-terminal domain of the 1-deoxy-D-xylulose-5-phosphate reductoisomerase enzyme. This domain forms a left handed super-helix.Domain
A, B
PF084361-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain (DXP_redisom_C)1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domainThis domain is found to the C-terminus of Pfam:PF02670 domains in bacterial and plant 1-deoxy-D-xylulose 5-phosphate reductoisomerases which catalyse the formation of 2-C-methyl-D-erythritol 4-phosphate from 1-deoxy-D-xylulose-5-phosphate in the pres ...This domain is found to the C-terminus of Pfam:PF02670 domains in bacterial and plant 1-deoxy-D-xylulose 5-phosphate reductoisomerases which catalyse the formation of 2-C-methyl-D-erythritol 4-phosphate from 1-deoxy-D-xylulose-5-phosphate in the presence of NADPH [1].
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
1-deoxy-D-xylulose 5-phosphate reductoisomerase