2C1X

Structure and activity of a flavonoid 3-O glucosyltransferase reveals the basis for plant natural product modification

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2c1xa1	Alpha and beta proteins (a/b)	UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	UDPGT-like	UDP glucose:flavonoid 3-o-glucosyltransferase	GRAPE (Vitis vinifera ) [TaxId: 29760 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Type B glycosyltransferase-like	8033606	3001586	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	UDPGT	e2c1xA2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: UDPGT	ECOD (1.6)
A	PLN02555	e2c1xA3	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PLN02555	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00201	UDP-glucoronosyl and UDP-glucosyl transferase (UDPGT)	UDP-glucoronosyl and UDP-glucosyl transferase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	UDP-GLUCOSE FLAVONOID 3-O GLYCOSYLTRANSFERASE	UDP-glycosyltransferase activity glycosyltransferase activity anthocyanidin 3-O-glucosyltransferase activity transferase activity glucosyltransferase activity hexosyltransferase activity catalytic activity UDP-glucosyltransferase activity flavonol 3-O-glucosyltransferase activity	carbohydrate derivative biosynthetic process cyanidin 3-O-glucoside biosynthetic process beta-glucoside biosynthetic process flavonoid metabolic process glycosyl compound metabolic process glycosyl compound biosynthetic process cyanidin 3-O-glucoside metabolic process glycoside metabolic process carbohydrate derivative metabolic process glycoside biosynthetic process biosynthetic process flavonoid biosynthetic process metabolic process cellular process carbohydrate derivative biosynthetic process cyanidin 3-O-glucoside biosynthetic process beta-glucoside biosynthetic process flavonoid metabolic process glycosyl compound metabolic process glycosyl compound biosynthetic process cyanidin 3-O-glucoside metabolic process glycoside metabolic process carbohydrate derivative metabolic process glycoside biosynthetic process biosynthetic process flavonoid biosynthetic process metabolic process cellular process beta-glucoside metabolic process pigment metabolic process pigment biosynthetic process quercetin O-glucoside metabolic process flavone biosynthetic process quercetin O-glucoside biosynthetic process flavone metabolic process anthocyanin-containing compound biosynthetic process anthocyanin-containing compound metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR035595	UDP-glycosyltransferase family, conserved site	Conserved Site
A	IPR002213	UDP-glucuronosyl/UDP-glucosyltransferase	Family
A	IPR050506	Plant_UDP-glycosyltransf	Unknown

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.