2G19

Cellular Oxygen Sensing: Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2)


Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad2g19a_ All beta proteins Double-stranded beta-helix Clavaminate synthase-like proly-4-hydroxylase (P4H, PHD) like HIF-P4H2, PHD2 human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
A2OG-FeII_Oxy_3e2g19A1 A: beta sandwichesX: jelly-rollH: Double-stranded beta-helix (From Topology)T: Double-stranded beta-helixF: 2OG-FeII_Oxy_3ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A2.60.120.620 Mainly Beta Sandwich Jelly Rolls q2cbj1_9rhob like domainCATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF136402OG-Fe(II) oxygenase superfamily (2OG-FeII_Oxy_3)2OG-Fe(II) oxygenase superfamilyThis family contains members of the 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily [1].Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
Egl nine homolog 1