2H5A

Complex of the enzyme PMM/PGM with xylose 1-phosphate

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Protein Modification Annotation

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A [auth X]	d2h5ax2	Alpha and beta proteins (a/b)	Phosphoglucomutase, first 3 domains	Phosphoglucomutase, first 3 domains	Phosphoglucomutase, first 3 domains	Phosphomannomutase/phosphoglucomutase, middle and C-terminal domain	(Pseudomonas aeruginosa ) [TaxId: 287 ],	SCOPe (2.08)
A [auth X]	d2h5ax1	Alpha and beta proteins (a/b)	Phosphoglucomutase, first 3 domains	Phosphoglucomutase, first 3 domains	Phosphoglucomutase, first 3 domains	Phosphomannomutase/phosphoglucomutase, N-terminal domain	(Pseudomonas aeruginosa ) [TaxId: 287 ],	SCOPe (2.08)
A [auth X]	d2h5ax4	Alpha and beta proteins (a+b)	TBP-like	Phosphoglucomutase, C-terminal domain	Phosphoglucomutase, C-terminal domain	Phosphomannomutase/phosphoglucomutase	(Pseudomonas aeruginosa ) [TaxId: 287 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A [auth X]	SCOP2B Superfamily	Phosphoglucomutase, first 3 domains	8038240	3001532	SCOP2B (2022-06-29)
A [auth X]	SCOP2B Superfamily	Phosphoglucomutase C-terminal domain-like	8038242	3000732	SCOP2B (2022-06-29)
A [auth X]	SCOP2B Superfamily	Phosphoglucomutase, first 3 domains	8038239	3001532	SCOP2B (2022-06-29)
A [auth X]	SCOP2B Superfamily	Phosphoglucomutase, first 3 domains	8038241	3001532	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth X]	PGM_PMM_IV	e2h5aX1	A: a+b two layers	X: TBP-like	H: Phosphoglucomutase, C-terminal domain (From Topology)	T: Phosphoglucomutase, C-terminal domain	F: PGM_PMM_IV	ECOD (1.6)
A [auth X]	PGM_PMM_I	e2h5aX2	A: a/b three-layered sandwiches	X: Phosphoglucomutase, first 3 domains (From Topology)	H: Phosphoglucomutase, first 3 domains (From Topology)	T: Phosphoglucomutase, first 3 domains	F: PGM_PMM_I	ECOD (1.6)
A [auth X]	PGM_PMM_II	e2h5aX3	A: a/b three-layered sandwiches	X: Phosphoglucomutase, first 3 domains (From Topology)	H: Phosphoglucomutase, first 3 domains (From Topology)	T: Phosphoglucomutase, first 3 domains	F: PGM_PMM_II	ECOD (1.6)
A [auth X]	PGM_PMM_III	e2h5aX4	A: a/b three-layered sandwiches	X: Phosphoglucomutase, first 3 domains (From Topology)	H: Phosphoglucomutase, first 3 domains (From Topology)	T: Phosphoglucomutase, first 3 domains	F: PGM_PMM_III	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A [auth X]	3.40.120.10	Alpha Beta	3-Layer(aba) Sandwich	Alpha-D-Glucose-1,6-Bisphosphate	Chain A, domain 3	CATH (4.3.0)
A [auth X]	3.30.310.50	Alpha Beta	2-Layer Sandwich	TATA-Binding Protein	Alpha-D-phosphohexomutase, C-terminal domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth X]	PF02878	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I (PGM_PMM_I)	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I	-	Domain
A [auth X]	PF02879	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II (PGM_PMM_II)	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II	-	Domain
A [auth X]	PF00408	Phosphoglucomutase/phosphomannomutase, C-terminal domain (PGM_PMM_IV)	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	Repeat
A [auth X]	PF02880	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III (PGM_PMM_III)	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth X]	Phosphomannomutase/phosphoglucomutase	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding phosphoglucomutase activity isomerase activity intramolecular phosphotransferase activity catalytic activity intramolecular transferase activity phosphomannomutase activity	lipopolysaccharide biosynthetic process carbohydrate derivative biosynthetic process carbohydrate metabolic process polysaccharide biosynthetic process carbohydrate biosynthetic process liposaccharide metabolic process lipid biosynthetic process carbohydrate derivative metabolic process primary metabolic process macromolecule biosynthetic process O antigen biosynthetic process lipopolysaccharide metabolic process O antigen metabolic process polysaccharide metabolic process biosynthetic process lipopolysaccharide biosynthetic process carbohydrate derivative biosynthetic process carbohydrate metabolic process polysaccharide biosynthetic process carbohydrate biosynthetic process liposaccharide metabolic process lipid biosynthetic process carbohydrate derivative metabolic process primary metabolic process macromolecule biosynthetic process O antigen biosynthetic process lipopolysaccharide metabolic process O antigen metabolic process polysaccharide metabolic process biosynthetic process metabolic process cellular process macromolecule metabolic process lipid metabolic process alginic acid biosynthetic process small molecule biosynthetic process oxoacid metabolic process carboxylic acid metabolic process alginic acid metabolic process organic acid biosynthetic process organic acid metabolic process carboxylic acid biosynthetic process small molecule metabolic process nucleoside phosphate metabolic process nucleotide-sugar metabolic process nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process organophosphate metabolic process organophosphate biosynthetic process nucleobase-containing small molecule metabolic process nucleoside phosphate biosynthetic process phosphate-containing compound metabolic process GDP-mannose biosynthetic process nucleotide-sugar biosynthetic process phosphorus metabolic process GDP-mannose metabolic process oligosaccharide metabolic process lipopolysaccharide core region metabolic process lipopolysaccharide core region biosynthetic process oligosaccharide biosynthetic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth X]	IPR005843	Alpha-D-phosphohexomutase, C-terminal	Domain
A [auth X]	IPR005846	Alpha-D-phosphohexomutase, alpha/beta/alpha domain III	Domain
A [auth X]	IPR005845	Alpha-D-phosphohexomutase, alpha/beta/alpha domain II	Domain
A [auth X]	IPR016055	Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III	Homologous Superfamily
A [auth X]	IPR016066	Alpha-D-phosphohexomutase, conserved site	Conserved Site
A [auth X]	IPR005844	Alpha-D-phosphohexomutase, alpha/beta/alpha domain I	Domain
A [auth X]	IPR005841	Alpha-D-phosphohexomutase superfamily	Family
A [auth X]	IPR036900	Alpha-D-phosphohexomutase, C-terminal domain superfamily	Homologous Superfamily

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
A [auth X]	SEP	Parent Component: SER RESID: AA0037 PSI-MOD : O-phospho-L-serine MOD:00046

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.