2IY8

Crystal structure of the sialyltransferase PM0188 with CMP-3FNeuAc and lactose

External Resource: Annotation


Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad2iy8a_ Alpha and beta proteins (a/b) UDP-Glycosyltransferase/glycogen phosphorylase UDP-Glycosyltransferase/glycogen phosphorylase Sialyltransferase-like Alpha-2,3/2,6-sialyltransferase/sialidase (Pasteurella multocida ) [TaxId: 747 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2 FamilySialyltransferase-like 8085112 4003276 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyType B glycosyltransferase-like 8085113 3001586 SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APM0188_Ce2iy8A2 A: a/b three-layered sandwichesX: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)T: UDP-Glycosyltransferase/glycogen phosphorylaseF: PM0188_CECOD (1.6)
APM0188_Ne2iy8A1 A: a/b three-layered sandwichesX: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)T: UDP-Glycosyltransferase/glycogen phosphorylaseF: PM0188_NECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.40.50.11120 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold Sialyltransferase, N-terminal GT-B Rossman nucleotide-binding domainCATH (4.3.0)
A3.40.50.11110 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold Sialyltransferase, C-terminal GT-B Rossman nucleotide-binding domainCATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF11477Sialyltransferase PMO188 (PM0188)Sialyltransferase PMO188- Family

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
IPR021574Sialyltransferase PMO188Family
IPR043078Sialyltransferase, N-terminal GT-B Rossman nucleotide-binding domainHomologous Superfamily