2OX9

Mouse Scavenger Receptor C-type Lectin carbohydrate-recognition domain.

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B	d2ox9b_	Alpha and beta proteins (a+b)	C-type lectin-like	C-type lectin-like	automated matches	automated matches	house mouse (Mus musculus ) [TaxId: 10090 ],	SCOPe (2.08)
C	d2ox9c_	Alpha and beta proteins (a+b)	C-type lectin-like	C-type lectin-like	automated matches	automated matches	house mouse (Mus musculus ) [TaxId: 10090 ],	SCOPe (2.08)
D	d2ox9d_	Alpha and beta proteins (a+b)	C-type lectin-like	C-type lectin-like	automated matches	automated matches	house mouse (Mus musculus ) [TaxId: 10090 ],	SCOPe (2.08)
A	d2ox9a_	Alpha and beta proteins (a+b)	C-type lectin-like	C-type lectin-like	automated matches	automated matches	house mouse (Mus musculus ) [TaxId: 10090 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	C-type lectin-like	8065468	3001261	SCOP2B (2022-06-29)
C	SCOP2 Family	C-type lectin domain	8065467	4002453	SCOP2 (2022-06-29)
C	SCOP2 Superfamily	C-type lectin-like	8065468	3001261	SCOP2 (2022-06-29)
D	SCOP2B Superfamily	C-type lectin-like	8065468	3001261	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	C-type lectin-like	8065468	3001261	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	Lectin_C	e2ox9B1	A: a+b complex topology	X: C-type lectin-like (From Homology)	H: C-type lectin-like	T: C-type lectin-like	F: Lectin_C	ECOD (1.6)
C	Lectin_C	e2ox9C1	A: a+b complex topology	X: C-type lectin-like (From Homology)	H: C-type lectin-like	T: C-type lectin-like	F: Lectin_C	ECOD (1.6)
D	Lectin_C	e2ox9D1	A: a+b complex topology	X: C-type lectin-like (From Homology)	H: C-type lectin-like	T: C-type lectin-like	F: Lectin_C	ECOD (1.6)
A	Lectin_C	e2ox9A1	A: a+b complex topology	X: C-type lectin-like (From Homology)	H: C-type lectin-like	T: C-type lectin-like	F: Lectin_C	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	3.10.100.10	Alpha Beta	Roll	Mannose-Binding Protein A	Chain A	CATH (4.3.0)
C	3.10.100.10	Alpha Beta	Roll	Mannose-Binding Protein A	Chain A	CATH (4.3.0)
D	3.10.100.10	Alpha Beta	Roll	Mannose-Binding Protein A	Chain A	CATH (4.3.0)
A	3.10.100.10	Alpha Beta	Roll	Mannose-Binding Protein A	Chain A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF00059	Lectin C-type domain (Lectin_C)	Lectin C-type domain	This family includes both long and short form C-type	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Collectin placenta 1	binding carbohydrate binding molecular transducer activity signaling receptor activity lipoprotein particle binding protein-containing complex binding protein-lipid complex binding low-density lipoprotein particle binding pattern recognition receptor activity cargo receptor activity scavenger receptor activity cation binding ion binding metal ion binding binding carbohydrate binding molecular transducer activity signaling receptor activity lipoprotein particle binding protein-containing complex binding protein-lipid complex binding low-density lipoprotein particle binding pattern recognition receptor activity cargo receptor activity scavenger receptor activity cation binding ion binding metal ion binding small molecule binding	response to stimulus immune response immune system process plasma membrane raft organization membrane organization cellular component organization plasma membrane organization cellular process cellular component organization or biogenesis membrane raft organization endomembrane system organization cellular response to nitrogen compound cellular response to stimulus cellular response to dsRNA response to stimulus immune response immune system process plasma membrane raft organization membrane organization cellular component organization plasma membrane organization cellular process cellular component organization or biogenesis membrane raft organization endomembrane system organization cellular response to nitrogen compound cellular response to stimulus cellular response to dsRNA cellular response to exogenous dsRNA cellular response to organic cyclic compound response to dsRNA response to nitrogen compound response to exogenous dsRNA cellular response to chemical stimulus response to chemical response to organic cyclic compound positive regulation of response to biotic stimulus regulation of cellular process pattern recognition receptor signaling pathway response to biotic stimulus intracellular signal transduction cell communication immune response-activating signaling pathway positive regulation of immune response regulation of immune system process signal transduction positive regulation of immune system process innate immune response-activating signaling pathway regulation of biological process response to other organism regulation of innate immune response response to external stimulus regulation of response to stimulus defense response to other organism positive regulation of defense response activation of innate immune response regulation of immune response activation of immune response cytoplasmic pattern recognition receptor signaling pathway regulation of defense response regulation of response to biotic stimulus biological process involved in interspecies interaction between organisms regulation of response to external stimulus intracellular receptor signaling pathway signaling positive regulation of biological process positive regulation of response to stimulus endolysosomal toll-like receptor signaling pathway positive regulation of response to external stimulus immune response-regulating signaling pathway regulation of response to stress response to stress innate immune response response to external biotic stimulus positive regulation of innate immune response defense response biological regulation defense response to symbiont toll-like receptor 3 signaling pathway defense response to bacterium response to bacterium phagocytosis, recognition localization import into cell transport phagocytosis cell recognition endocytosis establishment of localization vesicle-mediated transport	protein-containing complex collagen trimer cellular anatomical structure membrane cell periphery extracellular matrix external encapsulating structure collagen-containing extracellular matrix

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR008160	Collagen triple helix repeat	Repeat
A, B, C, D	IPR016187	C-type lectin fold	Homologous Superfamily
A, B, C, D	IPR033989	CD209-like, C-type lectin-like domain	Domain
A, B, C, D	IPR001304	C-type lectin-like	Domain
A, B, C, D	IPR018378	C-type lectin, conserved site	Conserved Site
A, B, C, D	IPR016186	C-type lectin-like/link domain superfamily	Homologous Superfamily
A, B, C, D	IPR050111	C-type lectin and snaclec domain-containing protein	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.