Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2 FamilyAldO C-terminal domain-like 8045165 4004332 SCOP2 (2022-06-29)
ASCOP2 FamilyFAD-linked oxidases, N-terminal domain 8057018 4002178 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyFAD-linked oxidases C-terminal domain-like 8057017 3001317 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyFAD-binding/transporter-associated domain-like 8057019 3000913 SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AALOe2vfrA2 A: a+b two layersX: Alpha-beta plaitsH: FAD-linked oxidases, C-terminal domain (From Topology)T: FAD-linked oxidases, C-terminal domainF: ALOECOD (1.6)
AFAD_binding_4e2vfrA1 A: a+b complex topologyX: FAD-binding domain-likeH: FAD-binding domain (From Topology)T: FAD-binding domainF: FAD_binding_4ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF04030D-arabinono-1,4-lactone oxidase (ALO)D-arabinono-1,4-lactone oxidase- Family
PF01565FAD binding domain (FAD_binding_4)FAD binding domainThis family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, call ...This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110 [1]. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyses the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyses the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan [2].
Domain