Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad2vpfa_ Small proteins Cystine-knot cytokines Cystine-knot cytokines Platelet-derived growth factor-like Vascular endothelial growth factor, VEGF human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Bd2vpfb_ Small proteins Cystine-knot cytokines Cystine-knot cytokines Platelet-derived growth factor-like Vascular endothelial growth factor, VEGF human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Cd2vpfc_ Small proteins Cystine-knot cytokines Cystine-knot cytokines Platelet-derived growth factor-like Vascular endothelial growth factor, VEGF human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Dd2vpfd_ Small proteins Cystine-knot cytokines Cystine-knot cytokines Platelet-derived growth factor-like Vascular endothelial growth factor, VEGF human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Ed2vpfe_ Small proteins Cystine-knot cytokines Cystine-knot cytokines Platelet-derived growth factor-like Vascular endothelial growth factor, VEGF human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Fd2vpff_ Small proteins Cystine-knot cytokines Cystine-knot cytokines Platelet-derived growth factor-like Vascular endothelial growth factor, VEGF human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Gd2vpfg_ Small proteins Cystine-knot cytokines Cystine-knot cytokines Platelet-derived growth factor-like Vascular endothelial growth factor, VEGF human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Hd2vpfh_ Small proteins Cystine-knot cytokines Cystine-knot cytokines Platelet-derived growth factor-like Vascular endothelial growth factor, VEGF human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APDGFe2vpfA1 A: few secondary structure elementsX: Cystine-knot cytokines (From Topology)H: Cystine-knot cytokines (From Topology)T: Cystine-knot cytokinesF: PDGFECOD (1.6)
BPDGFe2vpfB1 A: few secondary structure elementsX: Cystine-knot cytokines (From Topology)H: Cystine-knot cytokines (From Topology)T: Cystine-knot cytokinesF: PDGFECOD (1.6)
CPDGFe2vpfC1 A: few secondary structure elementsX: Cystine-knot cytokines (From Topology)H: Cystine-knot cytokines (From Topology)T: Cystine-knot cytokinesF: PDGFECOD (1.6)
DPDGFe2vpfD1 A: few secondary structure elementsX: Cystine-knot cytokines (From Topology)H: Cystine-knot cytokines (From Topology)T: Cystine-knot cytokinesF: PDGFECOD (1.6)
EPDGFe2vpfE1 A: few secondary structure elementsX: Cystine-knot cytokines (From Topology)H: Cystine-knot cytokines (From Topology)T: Cystine-knot cytokinesF: PDGFECOD (1.6)
FPDGFe2vpfF1 A: few secondary structure elementsX: Cystine-knot cytokines (From Topology)H: Cystine-knot cytokines (From Topology)T: Cystine-knot cytokinesF: PDGFECOD (1.6)
GPDGFe2vpfG1 A: few secondary structure elementsX: Cystine-knot cytokines (From Topology)H: Cystine-knot cytokines (From Topology)T: Cystine-knot cytokinesF: PDGFECOD (1.6)
HPDGFe2vpfH1 A: few secondary structure elementsX: Cystine-knot cytokines (From Topology)H: Cystine-knot cytokines (From Topology)T: Cystine-knot cytokinesF: PDGFECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D, E
PF00341PDGF/VEGF domain (PDGF)PDGF/VEGF domain- Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C, D, E
VASCULAR ENDOTHELIAL GROWTH FACTOR

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C, D, E
IPR029034Cystine-knot cytokineHomologous Superfamily
A, B, C, D, E
IPR036841Vascular endothelial growth factor, heparin-binding domain superfamilyHomologous Superfamily
A, B, C, D, E
IPR023581Platelet-derived growth factor, conserved siteConserved Site
A, B, C, D, E
IPR000072PDGF/VEGF domainDomain
A, B, C, D, E
IPR027928Vascular endothelial growth factor, heparin-binding domainDomain
A, B, C, D, E
IPR050507Platelet-derived/Vascular endothelial growth factorFamily

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
A, B, C, D, E
PharosP15692