Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
BSCOP2B Superfamily4Fe-4S ferredoxins 8087201 3000020 SCOP2B (2022-06-29)
E [auth F]SCOP2B Superfamily4Fe-4S ferredoxins 8087201 3000020 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AMolydop_bindinge2vpxA1 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: double psiF: Molydop_bindingECOD (1.6)
AMolybdop_Fe4S4e2vpxA3 A: a+b two layersX: Formate dehydrogenase/DMSO reductase, domain 1 (From Topology)H: Formate dehydrogenase/DMSO reductase, domain 1 (From Topology)T: Formate dehydrogenase/DMSO reductase, domain 1F: Molybdop_Fe4S4ECOD (1.6)
AMolybdopterin_2nde2vpxA2 A: a/b three-layered sandwichesX: Rossmann-likeH: Formate dehydrogenase/DMSO reductase, domains 2 and 3 (From Topology)T: Formate dehydrogenase/DMSO reductase, domains 2 and 3F: Molybdopterin_2ndECOD (1.6)
AMolybdopterin_1st_1e2vpxA4 A: a/b three-layered sandwichesX: Rossmann-likeH: Formate dehydrogenase/DMSO reductase, domains 2 and 3 (From Topology)T: Formate dehydrogenase/DMSO reductase, domains 2 and 3F: Molybdopterin_1st_1ECOD (1.6)
D [auth E]Molydop_bindinge2vpxE1 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: double psiF: Molydop_bindingECOD (1.6)
D [auth E]Molybdop_Fe4S4e2vpxE3 A: a+b two layersX: Formate dehydrogenase/DMSO reductase, domain 1 (From Topology)H: Formate dehydrogenase/DMSO reductase, domain 1 (From Topology)T: Formate dehydrogenase/DMSO reductase, domain 1F: Molybdop_Fe4S4ECOD (1.6)
D [auth E]Molybdopterin_2nde2vpxE4 A: a/b three-layered sandwichesX: Rossmann-likeH: Formate dehydrogenase/DMSO reductase, domains 2 and 3 (From Topology)T: Formate dehydrogenase/DMSO reductase, domains 2 and 3F: Molybdopterin_2ndECOD (1.6)
D [auth E]Molybdopterin_1st_1e2vpxE2 A: a/b three-layered sandwichesX: Rossmann-likeH: Formate dehydrogenase/DMSO reductase, domains 2 and 3 (From Topology)T: Formate dehydrogenase/DMSO reductase, domains 2 and 3F: Molybdopterin_1st_1ECOD (1.6)
BFer4_11e2vpxB1 A: a+b two layersX: 4Fe-4S ferredoxin (From Topology)H: 4Fe-4S ferredoxin (From Topology)T: 4Fe-4S ferredoxinF: Fer4_11ECOD (1.6)
BFer4_11_1e2vpxB2 A: a+b two layersX: 4Fe-4S ferredoxin (From Topology)H: 4Fe-4S ferredoxin (From Topology)T: 4Fe-4S ferredoxinF: Fer4_11_1ECOD (1.6)
E [auth F]Fer4_11e2vpxF2 A: a+b two layersX: 4Fe-4S ferredoxin (From Topology)H: 4Fe-4S ferredoxin (From Topology)T: 4Fe-4S ferredoxinF: Fer4_11ECOD (1.6)
E [auth F]Fer4_11_1e2vpxF1 A: a+b two layersX: 4Fe-4S ferredoxin (From Topology)H: 4Fe-4S ferredoxin (From Topology)T: 4Fe-4S ferredoxinF: Fer4_11_1ECOD (1.6)
CNrfD_2_Ce2vpxC2 A: alpha bundlesX: Transmembrane heme-binding four-helical bundle (From Homology)H: Transmembrane heme-binding four-helical bundleT: Transmembrane di-heme cytochromesF: NrfD_2_CECOD (1.6)
CNrfD_2e2vpxC1 A: alpha bundlesX: Transmembrane heme-binding four-helical bundle (From Homology)H: Transmembrane heme-binding four-helical bundleT: Transmembrane di-heme cytochromesF: NrfD_2ECOD (1.6)
F [auth G]NrfD_2_Ce2vpxG2 A: alpha bundlesX: Transmembrane heme-binding four-helical bundle (From Homology)H: Transmembrane heme-binding four-helical bundleT: Transmembrane di-heme cytochromesF: NrfD_2_CECOD (1.6)
F [auth G]NrfD_2e2vpxG1 A: alpha bundlesX: Transmembrane heme-binding four-helical bundle (From Homology)H: Transmembrane heme-binding four-helical bundleT: Transmembrane di-heme cytochromesF: NrfD_2ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A,
D [auth E]
PF01568Molydopterin dinucleotide binding domain (Molydop_binding)Molydopterin dinucleotide binding domainThis domain is found in various molybdopterin - containing oxidoreductases and tungsten formylmethanofuran dehydrogenase subunit d (FwdD) and molybdenum formylmethanofuran dehydrogenase subunit (FmdD); where the domain constitutes almost the entir ...This domain is found in various molybdopterin - containing oxidoreductases and tungsten formylmethanofuran dehydrogenase subunit d (FwdD) and molybdenum formylmethanofuran dehydrogenase subunit (FmdD); where the domain constitutes almost the entire subunit. The formylmethanofuran dehydrogenase catalyses the first step in methane formation from CO2 in methanogenic archaea and has a molybdopterin dinucleotide cofactor [1]. This domain corresponds to the C-terminal domain IV in dimethyl sulfoxide (DMSO)reductase which interacts with the 2-amino pyrimidone ring of both molybdopterin guanine dinucleotide molecules [2].
Domain
A,
D [auth E]
PF04879Molybdopterin oxidoreductase Fe4S4 domain (Molybdop_Fe4S4)Molybdopterin oxidoreductase Fe4S4 domainThis domain is found in formate dehydrogenase H for which the structure is known. This first domain (residues 1 to 60) of PDB:1aa6 is an Fe4S4 cluster just below the protein surface [1].Domain
A,
D [auth E]
PF00384Molybdopterin oxidoreductase (Molybdopterin)Molybdopterin oxidoreductase- Family
B,
E [auth F]
PF132474Fe-4S dicluster domain (Fer4_11)4Fe-4S dicluster domainSuperfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contai ...Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.
Domain
B,
E [auth F]
PF128004Fe-4S binding domain (Fer4_4)4Fe-4S binding domainThis superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.Domain