2Z4T
Crystal Structure of Vibrionaceae Photobacterium sp. JT-ISH-224 2,6-sialyltransferase in a Ternary Complex with Donor Product CMP and Accepter Substrate Lactose
Domain Annotation: ECOD Classification ECOD Database Homepage
| Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
|---|---|---|---|---|---|---|---|---|
| A | PKD_4 | e2z4tA2 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: PKD_4 | ECOD (1.6) |
| A | PM0188_C | e2z4tA1 | A: a/b three-layered sandwiches | X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology) | H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology) | T: UDP-Glycosyltransferase/glycogen phosphorylase | F: PM0188_C | ECOD (1.6) |
| A | PM0188_N | e2z4tA3 | A: a/b three-layered sandwiches | X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology) | H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology) | T: UDP-Glycosyltransferase/glycogen phosphorylase | F: PM0188_N | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
| Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
|---|---|---|---|---|---|---|
| A | 2.60.40.3010 | Mainly Beta | Sandwich | Immunoglobulin-like | CATH (4.3.0) | |
| A | 3.40.50.11120 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Sialyltransferase, N-terminal GT-B Rossman nucleotide-binding domain | CATH (4.3.0) |
| A | 3.40.50.11110 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Sialyltransferase, C-terminal GT-B Rossman nucleotide-binding domain | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
| Chains | Accession | Name | Description | Comments | Source |
|---|---|---|---|---|---|
| PF11477 | Sialyltransferase PMO188 (PM0188) | Sialyltransferase PMO188 | - | Family | |
| PF22352 | K319L-like, PKD domain (K319L-like_PKD) | K319L-like, PKD domain | This entry represents the PKD domain of Dyslexia-associated protein KIAA0319-like protein, in which it is found in four copies. This entry also includes Kunitz-type protease inhibitor 1 and LRP11 from human. | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
| Chains | Polymer | Molecular Function | Biological Process | Cellular Component |
|---|---|---|---|---|
| Beta-galactoside alpha-2,6-sialyltransferase | - | - |
InterPro: Protein Family Classification InterPro Database Homepage
| Chains | Accession | Name | Type |
|---|---|---|---|
| IPR021574 | Sialyltransferase PMO188 | Family | |
| IPR043078 | Sialyltransferase, N-terminal GT-B Rossman nucleotide-binding domain | Homologous Superfamily |
