2ZZV

Crystal Structure of a Periplasmic Substrate Binding Protein in Complex with Calcium and Lactate

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B	d2zzvb_	Alpha and beta proteins (a/b)	Periplasmic binding protein-like II	Periplasmic binding protein-like II	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
A	d2zzva_	Alpha and beta proteins (a/b)	Periplasmic binding protein-like II	Periplasmic binding protein-like II	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	DctP	e2zzvB1	A: a/b three-layered sandwiches	X: Periplasmic binding protein-like II (From Topology)	H: Periplasmic binding protein-like II (From Topology)	T: Periplasmic binding protein-like II	F: DctP	ECOD (1.6)
A	DctP	e2zzvA1	A: a/b three-layered sandwiches	X: Periplasmic binding protein-like II (From Topology)	H: Periplasmic binding protein-like II (From Topology)	T: Periplasmic binding protein-like II	F: DctP	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	3.40.190.170	Alpha Beta	3-Layer(aba) Sandwich	D-Maltodextrin-Binding Protein	domain 2	CATH (4.3.0)
A	3.40.190.170	Alpha Beta	3-Layer(aba) Sandwich	D-Maltodextrin-Binding Protein	domain 2	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF03480	Bacterial extracellular solute-binding protein, family 7 (DctP)	Bacterial extracellular solute-binding protein, family 7	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	ABC transporter, solute-binding protein	cation binding ion binding binding calcium ion binding metal ion binding small molecule binding identical protein binding protein binding protein homodimerization activity protein dimerization activity transition metal ion binding zinc ion binding	lactate transport organic acid transport localization organic anion transport monocarboxylic acid transport carboxylic acid transport transport organic hydroxy compound transport establishment of localization transmembrane transport cellular process	cellular anatomical structure periplasmic space protein-containing complex tripartite ATP-independent periplasmic transporter complex transporter complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR018389	TRAP transporter solute receptor DctP	Family
A, B	IPR038404	TRAP transporter solute receptor DctP superfamily	Homologous Superfamily
A, B	IPR006311	Twin-arginine translocation pathway, signal sequence	Conserved Site
A, B	IPR026289	Solute binding protein, TakP-like	Family
A, B	IPR041721	Lactate-binding periplasmic protein TTHA0766	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.