2VBV

Riboflavin kinase Mj0056 from Methanocaldococcus jannaschii in complex with CDP and FMN

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2vbva_	All beta proteins	Reductase/isomerase/elongation factor common domain	Riboflavin kinase-like	CTP-dependent riboflavin kinase-like	CTP-dependent riboflavin kinase, Rfk	(Methanocaldococcus jannaschii ) [TaxId: 2190 ],	SCOPe (2.08)
B	d2vbvb_	All beta proteins	Reductase/isomerase/elongation factor common domain	Riboflavin kinase-like	CTP-dependent riboflavin kinase-like	CTP-dependent riboflavin kinase, Rfk	(Methanocaldococcus jannaschii ) [TaxId: 2190 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Riboflavin kinase-like	8037441	3000067	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Riboflavin kinase-like	8037441	3000067	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	CTP-dep_RFKase	e2vbvA1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: CTP-dep_RFKase	ECOD (1.6)
B	CTP-dep_RFKase	e2vbvB1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: CTP-dep_RFKase	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.40.30.30	Mainly Beta	Beta Barrel	Elongation Factor Tu (Ef-tu)	domain 3	CATH (4.3.0)
B	2.40.30.30	Mainly Beta	Beta Barrel	Elongation Factor Tu (Ef-tu)	domain 3	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF01982	Domain of unknown function DUF120 (CTP-dep_RFKase)	Domain of unknown function DUF120	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	RIBOFLAVIN KINASE	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding riboflavin kinase activity kinase activity transferase activity catalytic activity phosphotransferase activity, alcohol group as acceptor transferase activity, transferring phosphorus-containing groups nucleoside phosphate binding organic cyclic compound binding cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding riboflavin kinase activity kinase activity transferase activity catalytic activity phosphotransferase activity, alcohol group as acceptor transferase activity, transferring phosphorus-containing groups nucleoside phosphate binding organic cyclic compound binding nucleotide binding heterocyclic compound binding	ribose phosphate metabolic process nucleotide biosynthetic process flavin-containing compound metabolic process carbohydrate derivative metabolic process nucleobase-containing compound metabolic process ribonucleotide biosynthetic process ribonucleotide metabolic process ribonucleoside monophosphate metabolic process nucleobase-containing small molecule metabolic process phosphate-containing compound metabolic process small molecule metabolic process FMN metabolic process phosphorus metabolic process ribose phosphate biosynthetic process ribose phosphate metabolic process nucleotide biosynthetic process flavin-containing compound metabolic process carbohydrate derivative metabolic process nucleobase-containing compound metabolic process ribonucleotide biosynthetic process ribonucleotide metabolic process ribonucleoside monophosphate metabolic process nucleobase-containing small molecule metabolic process phosphate-containing compound metabolic process small molecule metabolic process FMN metabolic process phosphorus metabolic process ribose phosphate biosynthetic process nucleoside monophosphate metabolic process nucleoside phosphate metabolic process carbohydrate derivative biosynthetic process cellular metabolic process primary metabolic process nucleobase-containing compound biosynthetic process nucleotide metabolic process nucleoside monophosphate biosynthetic process flavin-containing compound biosynthetic process biosynthetic process FMN biosynthetic process organophosphate metabolic process organophosphate biosynthetic process nucleoside phosphate biosynthetic process metabolic process cellular process ribonucleoside monophosphate biosynthetic process water-soluble vitamin biosynthetic process small molecule biosynthetic process cellular biosynthetic process vitamin biosynthetic process riboflavin biosynthetic process vitamin metabolic process water-soluble vitamin metabolic process riboflavin metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR023465	Riboflavin kinase domain superfamily	Homologous Superfamily
A, B	IPR023470	Riboflavin kinase, archaeal	Family
A, B	IPR053397	Archaeal Riboflavin Kinase	Family
A, B	IPR023602	Riboflavin kinase domain, CTP-dependent	Domain
A, B	IPR039063	Riboflavin kinase, CTP-dependent	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.