2X67

The ternary complex of PrnB (the second enzyme in pyrrolnitrin biosynthesis pathway), tryptophan and cyanide

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	DUF1864_C	e2x67A1	A: alpha bundles	X: Indolic compounds 2,3-dioxygenase-like (From Topology)	H: Indolic compounds 2,3-dioxygenase-like (From Topology)	T: Indolic compounds 2,3-dioxygenase-like	F: DUF1864_C	ECOD (1.6)
A	DUF1864_N	e2x67A2	A: alpha superhelices	X: Indoleamine 2,3-dioxygenase N-terminal subdomain (From Topology)	H: Indoleamine 2,3-dioxygenase N-terminal subdomain (From Topology)	T: Indoleamine 2,3-dioxygenase N-terminal subdomain	F: DUF1864_N	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.20.58.1320	Mainly Alpha	Up-down Bundle	Methane Monooxygenase Hydroxylase	Chain G, domain 1	CATH (4.3.0)
A	1.20.58.480	Mainly Alpha	Up-down Bundle	Methane Monooxygenase Hydroxylase	Chain G, domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF08933	Monodechloroaminopyrrolnitrin synthase PrnB (PrnB)	Monodechloroaminopyrrolnitrin synthase PrnB	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	PRNB	oxidoreductase activity catalytic activity binding organic cyclic compound binding tetrapyrrole binding heme binding cation binding ion binding metal ion binding small molecule binding	catabolic process oxoacid metabolic process aromatic amino acid family catabolic process indole-containing compound metabolic process amino acid metabolic process organic acid catabolic process organic acid metabolic process alpha-amino acid metabolic process cellular catabolic process non-proteinogenic amino acid metabolic process cellular ketone metabolic process carboxylic acid catabolic process indolalkylamine metabolic process small molecule metabolic process catabolic process oxoacid metabolic process aromatic amino acid family catabolic process indole-containing compound metabolic process amino acid metabolic process organic acid catabolic process organic acid metabolic process alpha-amino acid metabolic process cellular catabolic process non-proteinogenic amino acid metabolic process cellular ketone metabolic process carboxylic acid catabolic process indolalkylamine metabolic process small molecule metabolic process amino acid catabolic process aromatic amino acid metabolic process benzene-containing compound metabolic process cellular metabolic process carboxylic acid metabolic process primary metabolic process amine metabolic process kynurenine metabolic process tryptophan catabolic process to kynurenine alpha-amino acid catabolic process indole-containing compound catabolic process tryptophan catabolic process metabolic process cellular process small molecule catabolic process biogenic amine metabolic process antibiotic metabolic process biosynthetic process antibiotic biosynthetic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR015029	Monodechloroaminopyrrolnitrin synthase PrnB	Family
A	IPR037217	Tryptophan/Indoleamine 2,3-dioxygenase-like	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.