3A0C

Crystal Structure of an anti-HIV mannose-binding lectin from Polygonatum cyrtonema Hua

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3a0ca_	All beta proteins	beta-Prism II	alpha-D-mannose-specific plant lectins	automated matches	automated matches	(Polygonatum cyrtonema ) [TaxId: 195526 ],	SCOPe (2.08)
B	d3a0cb_	All beta proteins	beta-Prism II	alpha-D-mannose-specific plant lectins	automated matches	automated matches	(Polygonatum cyrtonema ) [TaxId: 195526 ],	SCOPe (2.08)
D	d3a0cd_	All beta proteins	beta-Prism II	alpha-D-mannose-specific plant lectins	automated matches	automated matches	(Polygonatum cyrtonema ) [TaxId: 195526 ],	SCOPe (2.08)
C	d3a0cc_	All beta proteins	beta-Prism II	alpha-D-mannose-specific plant lectins	automated matches	automated matches	(Polygonatum cyrtonema ) [TaxId: 195526 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	alpha-D-mannose-specific plant lectins	8079827	3001730	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	alpha-D-mannose-specific plant lectins	8079827	3001730	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	alpha-D-mannose-specific plant lectins	8079827	3001730	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	alpha-D-mannose-specific plant lectins	8079827	3001730	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	B_lectin	e3a0cA1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-Prism II (From Topology)	T: beta-Prism II	F: B_lectin	ECOD (1.6)
B	B_lectin	e3a0cB1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-Prism II (From Topology)	T: beta-Prism II	F: B_lectin	ECOD (1.6)
D	B_lectin	e3a0cD1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-Prism II (From Topology)	T: beta-Prism II	F: B_lectin	ECOD (1.6)
C	B_lectin	e3a0cC1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-Prism II (From Topology)	T: beta-Prism II	F: B_lectin	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.90.10.10	Mainly Beta	Orthogonal Prism	Agglutinin, subunit A	Bulb-type lectin domain	CATH (4.3.0)
B	2.90.10.10	Mainly Beta	Orthogonal Prism	Agglutinin, subunit A	Bulb-type lectin domain	CATH (4.3.0)
D	2.90.10.10	Mainly Beta	Orthogonal Prism	Agglutinin, subunit A	Bulb-type lectin domain	CATH (4.3.0)
C	2.90.10.10	Mainly Beta	Orthogonal Prism	Agglutinin, subunit A	Bulb-type lectin domain	CATH (4.3.0)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Mannose/sialic acid-binding lectin	binding carbohydrate binding	biological process involved in interspecies interaction between organisms response to stimulus response to other organism response to external stimulus response to external biotic stimulus response to biotic stimulus	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR001480	Bulb-type lectin domain	Domain
A, B, C, D	IPR036426	Bulb-type lectin domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.