3DAB
Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
B | SCOP2B Superfamily | p53 TAD | 8093389 | 3002701 | SCOP2B (2022-06-29) |
D | SCOP2B Superfamily | p53 TAD | 8093389 | 3002701 | SCOP2B (2022-06-29) |
F | SCOP2B Superfamily | p53 TAD | 8093389 | 3002701 | SCOP2B (2022-06-29) |
H | SCOP2B Superfamily | p53 TAD | 8093389 | 3002701 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | SWIB/MDM2 domain-like | 8082225 | 3000287 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | SWIB/MDM2 domain-like | 8082225 | 3000287 | SCOP2B (2022-06-29) |
E | SCOP2B Superfamily | SWIB/MDM2 domain-like | 8082225 | 3000287 | SCOP2B (2022-06-29) |
G | SCOP2B Superfamily | SWIB/MDM2 domain-like | 8082225 | 3000287 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | SWIB | e3dabA1 | A: alpha arrays | X: SWIB/MDM2 domain (From Topology) | H: SWIB/MDM2 domain (From Topology) | T: SWIB/MDM2 domain | F: SWIB | ECOD (1.6) |
C | SWIB | e3dabC1 | A: alpha arrays | X: SWIB/MDM2 domain (From Topology) | H: SWIB/MDM2 domain (From Topology) | T: SWIB/MDM2 domain | F: SWIB | ECOD (1.6) |
E | SWIB | e3dabE1 | A: alpha arrays | X: SWIB/MDM2 domain (From Topology) | H: SWIB/MDM2 domain (From Topology) | T: SWIB/MDM2 domain | F: SWIB | ECOD (1.6) |
G | SWIB | e3dabG1 | A: alpha arrays | X: SWIB/MDM2 domain (From Topology) | H: SWIB/MDM2 domain (From Topology) | T: SWIB/MDM2 domain | F: SWIB | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 1.10.245.10 | Mainly Alpha | Orthogonal Bundle | MDM2 | SWIB/MDM2 domain | CATH (4.3.0) |
C | 1.10.245.10 | Mainly Alpha | Orthogonal Bundle | MDM2 | SWIB/MDM2 domain | CATH (4.3.0) |
E | 1.10.245.10 | Mainly Alpha | Orthogonal Bundle | MDM2 | SWIB/MDM2 domain | CATH (4.3.0) |
G | 1.10.245.10 | Mainly Alpha | Orthogonal Bundle | MDM2 | SWIB/MDM2 domain | CATH (4.3.0) |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR012346 | p53/RUNT-type transcription factor, DNA-binding domain superfamily | Homologous Superfamily | |
IPR002117 | p53 tumour suppressor family | Family | |
IPR013872 | p53 transactivation domain | Domain | |
IPR036674 | p53-like tetramerisation domain superfamily | Homologous Superfamily | |
IPR011615 | p53, DNA-binding domain | Domain | |
IPR008967 | p53-like transcription factor, DNA-binding domain superfamily | Homologous Superfamily | |
IPR010991 | p53, tetramerisation domain | Domain | |
IPR040926 | Cellular tumor antigen p53, transactivation domain 2 | Domain | |
IPR051652 | MDM2/MDM4 and MUL1 | Family | |
IPR003121 | SWIB/MDM2 domain | Domain | |
IPR016495 | p53 negative regulator Mdm2/Mdm4 | Family | |
IPR036443 | Zinc finger, RanBP2-type superfamily | Homologous Superfamily | |
IPR036885 | SWIB/MDM2 domain superfamily | Homologous Superfamily | |
IPR013083 | Zinc finger, RING/FYVE/PHD-type | Homologous Superfamily | |
IPR001876 | Zinc finger, RanBP2-type | Domain | |
IPR001841 | Zinc finger, RING-type | Domain | |
IPR015458 | MDM4 | Family |