Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyHAD-like 8081288 3001890 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyHAD-like 8081288 3001890 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyHAD-like 8081288 3001890 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyHAD-like 8081288 3001890 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AHydrolase_3_1e3e8mA1 A: a/b three-layered sandwichesX: HAD domain-likeH: HAD domain-relatedT: HAD-likeF: Hydrolase_3_1ECOD (1.6)
BHydrolase_3_1e3e8mB1 A: a/b three-layered sandwichesX: HAD domain-likeH: HAD domain-relatedT: HAD-likeF: Hydrolase_3_1ECOD (1.6)
CHydrolase_3_1e3e8mC1 A: a/b three-layered sandwichesX: HAD domain-likeH: HAD domain-relatedT: HAD-likeF: Hydrolase_3_1ECOD (1.6)
DHydrolase_3_1e3e8mD1 A: a/b three-layered sandwichesX: HAD domain-likeH: HAD domain-relatedT: HAD-likeF: Hydrolase_3_1ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.40.50.1000 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold HAD superfamily/HAD-likeCATH (4.3.0)
B3.40.50.1000 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold HAD superfamily/HAD-likeCATH (4.3.0)
C3.40.50.1000 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold HAD superfamily/HAD-likeCATH (4.3.0)
D3.40.50.1000 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold HAD superfamily/HAD-likeCATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D
PF00702haloacid dehalogenase-like hydrolase (Hydrolase)haloacid dehalogenase-like hydrolaseThis family is structurally different from the alpha/beta hydrolase family (Pfam:PF00561). This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases. The structure of the family consists of two domains. One is an inserted fo ...This family is structurally different from the alpha/beta hydrolase family (Pfam:PF00561). This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases. The structure of the family consists of two domains. One is an inserted four helix bundle, which is the least well conserved region of the alignment, between residues 16 and 96 of Swiss:P24069. The rest of the fold is composed of the core alpha/beta domain [1]. Those members with the characteristic DxD triad at the N-terminus are probably phosphatidylglycerolphosphate (PGP) phosphatases involved in cardiolipin biosynthesis in the mitochondria [2].
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C, D
Acylneuraminate cytidylyltransferase - -

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C, D
IPR050793CMP-NeuNAc synthaseFamily
A, B, C, D
IPR006549HAD-superfamily hydrolase,subfamily IIIADomain
A, B, C, D
IPR036412HAD-like superfamilyHomologous Superfamily
A, B, C, D
IPR023214HAD superfamilyHomologous Superfamily
A, B, C, D
IPR010023KdsC familyFamily