3EM0

Crystal structure of Zebrafish Ileal Bile Acid-Bindin Protein complexed with cholic acid (crystal form B).

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3em0a1	All beta proteins	Lipocalins	Lipocalins	automated matches	automated matches	leopard danio,zebra danio,zebra fish (Danio rerio ) [TaxId: 7955 ],	SCOPe (2.08)
A	d3em0a2	Artifacts	Tags	Tags	Tags	N-terminal Tags	leopard danio,zebra danio,zebra fish (Danio rerio ) [TaxId: 7955 ],	SCOPe (2.08)
B	d3em0b1	All beta proteins	Lipocalins	Lipocalins	automated matches	automated matches	leopard danio,zebra danio,zebra fish (Danio rerio ) [TaxId: 7955 ],	SCOPe (2.08)
B	d3em0b3	Artifacts	Tags	Tags	Tags	C-terminal Tags	leopard danio,zebra danio,zebra fish (Danio rerio ) [TaxId: 7955 ],	SCOPe (2.08)
B	d3em0b2	Artifacts	Tags	Tags	Tags	N-terminal Tags	leopard danio,zebra danio,zebra fish (Danio rerio ) [TaxId: 7955 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Lipocalins	8062833	3001332	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Lipocalins	8062833	3001332	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Lipocalin_7	e3em0A1	A: beta barrels	X: Lipocalins/Streptavidin	H: Lipocalins (From Topology)	T: Lipocalins	F: Lipocalin_7	ECOD (1.6)
B	Lipocalin_7	e3em0B1	A: beta barrels	X: Lipocalins/Streptavidin	H: Lipocalins (From Topology)	T: Lipocalins	F: Lipocalin_7	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.40.128.20	Mainly Beta	Beta Barrel	Lipocalin	Calycin beta-barrel core domain	CATH (4.3.0)
B	2.40.128.20	Mainly Beta	Beta Barrel	Lipocalin	Calycin beta-barrel core domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF14651	Lipocalin / cytosolic fatty-acid binding protein family (Lipocalin_7)	Lipocalin / cytosolic fatty-acid binding protein family	Lipocalins are transporters for small hydrophobic molecules, such as lipids, steroid hormones, bilins, and retinoids. The family also encompasses the enzyme prostaglandin D synthase (EC:5.3.99.2).	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Ileal Bile Acid-Binding Protein	fatty acid binding organic acid binding binding ion binding anion binding lipid binding carboxylic acid binding monocarboxylic acid binding small molecule binding bile acid binding	organic anion transport carboxylic acid transport transport lipid localization lipid transport establishment of localization organic acid transport localization monocarboxylic acid transport fatty acid transport macromolecule localization	cellular anatomical structure intracellular anatomical structure cytoplasm cytosol membrane membrane-bounded organelle intracellular organelle organelle nucleus intracellular membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR012674	Calycin	Homologous Superfamily
A, B	IPR000463	Cytosolic fatty-acid binding	Domain
A, B	IPR031259	Intracellular lipid binding protein	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.