Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyRetrovirus capsid dimerization domain-like 8037182 3001819 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AGag_p24_Ce3h47A4 A: alpha bundlesX: Retrovirus capsid proteinH: Retrovirus capsid protein-C (From Topology)T: Retrovirus capsid protein-CF: Gag_p24_CECOD (1.6)
AGag_p24_Ne3h47A3 A: alpha bundlesX: Retrovirus capsid proteinH: Retrovirus capsid protein N-terminal domain (From Topology)T: Retrovirus capsid protein N-terminal domainF: Gag_p24_NECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF19317Gag protein p24 C-terminal domain (Gag_p24_C)Gag protein p24 C-terminal domainp24 forms inner protein layer of the nucleocapsid. ELISA tests for p24 is the most commonly used method to demonstrate virus replication both in vivo and in vitro.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
Capsid protein p24

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
IPR036397Ribonuclease H superfamilyHomologous Superfamily
IPR043128Reverse transcriptase/Diguanylate cyclase domainHomologous Superfamily
IPR001995Peptidase A2A, retrovirus, catalyticDomain
IPR001878Zinc finger, CCHC-typeDomain
IPR008919Retrovirus capsid, N-terminalHomologous Superfamily
IPR012344Matrix protein, lentiviral and alpha-retroviral, N-terminalHomologous Superfamily
IPR036862Integrase, C-terminal domain superfamily, retroviralHomologous Superfamily
IPR018061RetropepsinsDomain
IPR010661Reverse transcriptase thumbDomain
IPR002156Ribonuclease H domainDomain
IPR036875Zinc finger, CCHC-type superfamilyHomologous Superfamily
IPR003308Integrase, N-terminal zinc-binding domainDomain
IPR001584Integrase, catalytic coreDomain
IPR045345Retroviral nucleocapsid Gag protein p24, C-terminal domainDomain
IPR010999Retroviral matrix proteinHomologous Superfamily
IPR021109Aspartic peptidase domain superfamilyHomologous Superfamily
IPR001969Aspartic peptidase, active siteActive Site
IPR012337Ribonuclease H-like superfamilyHomologous Superfamily
IPR017856Integrase-like, N-terminalHomologous Superfamily
IPR000071Immunodeficiency lentiviral matrix, N-terminalDomain
IPR043502DNA/RNA polymerase superfamilyHomologous Superfamily
IPR001037Integrase, C-terminal, retroviralDomain
IPR034170Retropepsin-like catalytic domainDomain
IPR000477Reverse transcriptase domainDomain
IPR010659Reverse transcriptase connectionDomain
IPR008916Retrovirus capsid, C-terminalHomologous Superfamily