Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyALDH-like 8033787 3001479 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyALDH-like 8033787 3001479 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyALDH-like 8033787 3001479 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyALDH-like 8033787 3001479 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyALDH-like 8033787 3001479 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyALDH-like 8033787 3001479 SCOP2B (2022-06-29)
GSCOP2B SuperfamilyALDH-like 8033787 3001479 SCOP2B (2022-06-29)
HSCOP2B SuperfamilyALDH-like 8033787 3001479 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AAldedh_2nde3n82A2 A: a/b three-layered sandwichesX: ALDH-like (From Topology)H: ALDH-like (From Topology)T: ALDH-likeF: Aldedh_2ndECOD (1.6)
AAldedh_1st_1e3n82A1 A: a/b three-layered sandwichesX: ALDH-like (From Topology)H: ALDH-like (From Topology)T: ALDH-likeF: Aldedh_1st_1ECOD (1.6)
BAldedh_2nde3n82B2 A: a/b three-layered sandwichesX: ALDH-like (From Topology)H: ALDH-like (From Topology)T: ALDH-likeF: Aldedh_2ndECOD (1.6)
BAldedh_1st_1e3n82B1 A: a/b three-layered sandwichesX: ALDH-like (From Topology)H: ALDH-like (From Topology)T: ALDH-likeF: Aldedh_1st_1ECOD (1.6)
CAldedh_2nde3n82C2 A: a/b three-layered sandwichesX: ALDH-like (From Topology)H: ALDH-like (From Topology)T: ALDH-likeF: Aldedh_2ndECOD (1.6)
CAldedh_1st_1e3n82C1 A: a/b three-layered sandwichesX: ALDH-like (From Topology)H: ALDH-like (From Topology)T: ALDH-likeF: Aldedh_1st_1ECOD (1.6)
DAldedh_2nde3n82D1 A: a/b three-layered sandwichesX: ALDH-like (From Topology)H: ALDH-like (From Topology)T: ALDH-likeF: Aldedh_2ndECOD (1.6)
DAldedh_1st_1e3n82D2 A: a/b three-layered sandwichesX: ALDH-like (From Topology)H: ALDH-like (From Topology)T: ALDH-likeF: Aldedh_1st_1ECOD (1.6)
EAldedh_2nde3n82E1 A: a/b three-layered sandwichesX: ALDH-like (From Topology)H: ALDH-like (From Topology)T: ALDH-likeF: Aldedh_2ndECOD (1.6)
EAldedh_1st_1e3n82E2 A: a/b three-layered sandwichesX: ALDH-like (From Topology)H: ALDH-like (From Topology)T: ALDH-likeF: Aldedh_1st_1ECOD (1.6)
FAldedh_2nde3n82F1 A: a/b three-layered sandwichesX: ALDH-like (From Topology)H: ALDH-like (From Topology)T: ALDH-likeF: Aldedh_2ndECOD (1.6)
FAldedh_1st_1e3n82F2 A: a/b three-layered sandwichesX: ALDH-like (From Topology)H: ALDH-like (From Topology)T: ALDH-likeF: Aldedh_1st_1ECOD (1.6)
GAldedh_2nde3n82G1 A: a/b three-layered sandwichesX: ALDH-like (From Topology)H: ALDH-like (From Topology)T: ALDH-likeF: Aldedh_2ndECOD (1.6)
GAldedh_1st_1e3n82G2 A: a/b three-layered sandwichesX: ALDH-like (From Topology)H: ALDH-like (From Topology)T: ALDH-likeF: Aldedh_1st_1ECOD (1.6)
HAldedh_2nde3n82H1 A: a/b three-layered sandwichesX: ALDH-like (From Topology)H: ALDH-like (From Topology)T: ALDH-likeF: Aldedh_2ndECOD (1.6)
HAldedh_1st_1e3n82H2 A: a/b three-layered sandwichesX: ALDH-like (From Topology)H: ALDH-like (From Topology)T: ALDH-likeF: Aldedh_1st_1ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.40.605.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase Chain A, domain 1CATH (4.3.0)
A3.40.309.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase Chain A, domain 2CATH (4.3.0)
B3.40.605.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase Chain A, domain 1CATH (4.3.0)
B3.40.309.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase Chain A, domain 2CATH (4.3.0)
C3.40.605.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase Chain A, domain 1CATH (4.3.0)
C3.40.309.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase Chain A, domain 2CATH (4.3.0)
D3.40.605.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase Chain A, domain 1CATH (4.3.0)
D3.40.309.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase Chain A, domain 2CATH (4.3.0)
E3.40.605.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase Chain A, domain 1CATH (4.3.0)
E3.40.309.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase Chain A, domain 2CATH (4.3.0)
F3.40.605.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase Chain A, domain 1CATH (4.3.0)
F3.40.309.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase Chain A, domain 2CATH (4.3.0)
G3.40.605.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase Chain A, domain 1CATH (4.3.0)
G3.40.309.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase Chain A, domain 2CATH (4.3.0)
H3.40.605.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase Chain A, domain 1CATH (4.3.0)
H3.40.309.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase Chain A, domain 2CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D, E
PF00171Aldehyde dehydrogenase family (Aldedh)Aldehyde dehydrogenase family- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C, D, E
Aldehyde dehydrogenase, mitochondrial

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C, D, E
IPR015590Aldehyde dehydrogenase domainDomain
A, B, C, D, E
IPR016161Aldehyde/histidinol dehydrogenaseHomologous Superfamily
A, B, C, D, E
IPR016162Aldehyde dehydrogenase, N-terminalHomologous Superfamily
A, B, C, D, E
IPR029510Aldehyde dehydrogenase, glutamic acid active siteConserved Site
A, B, C, D, E
IPR016163Aldehyde dehydrogenase, C-terminalHomologous Superfamily
A, B, C, D, E
IPR016160Aldehyde dehydrogenase, cysteine active siteConserved Site

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
A, B, C, D, E
PharosP05091