3O8Y
Stable-5-Lipoxygenase
External Resource: Annotation
- Domain Annotation: SCOP/SCOPe Classification
- Domain Annotation: SCOP2 Classification
- Domain Annotation: ECOD Classification
- Domain Annotation: CATH
- Protein Family Annotation
- Gene Ontology: Gene Product Annotation
- InterPro: Protein Family Classification
- Pharos: Disease Associations
- Membrane Protein Annotation: OPM
- Membrane Protein Annotation: mpstruc
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | d3o8yb2 | All alpha proteins | Lipoxigenase | Lipoxigenase | automated matches | automated matches | human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
B | d3o8yb1 | All beta proteins | Lipase/lipooxygenase domain (PLAT/LH2 domain) | Lipase/lipooxygenase domain (PLAT/LH2 domain) | automated matches | automated matches | human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2B Superfamily | Lipase/lipooxygenase domain (PLAT/LH2 domain) | 8101094 | 3001168 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | Lipoxygenase | 8098328 | 3001410 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | Lipoxygenase | 8098328 | 3001410 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | Lipase/lipooxygenase domain (PLAT/LH2 domain) | 8101094 | 3001168 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | PLAT,RNAse_Pc_like | e3o8yA2 | A: beta sandwiches | X: jelly-roll | H: Lipase/lipooxygenase domain (PLAT/LH2 domain) (From Topology) | T: Lipase/lipooxygenase domain (PLAT/LH2 domain) | F: PLAT,RNAse_Pc_like | ECOD (1.6) |
A | Lipoxygenase | e3o8yA1 | A: alpha bundles | X: Lipoxygenase (From Topology) | H: Lipoxygenase (From Topology) | T: Lipoxygenase | F: Lipoxygenase | ECOD (1.6) |
B | PLAT | e3o8yB6 | A: beta sandwiches | X: jelly-roll | H: Lipase/lipooxygenase domain (PLAT/LH2 domain) (From Topology) | T: Lipase/lipooxygenase domain (PLAT/LH2 domain) | F: PLAT | ECOD (1.6) |
B | Lipoxygenase | e3o8yB5 | A: alpha bundles | X: Lipoxygenase (From Topology) | H: Lipoxygenase (From Topology) | T: Lipoxygenase | F: Lipoxygenase | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 2.60.60.20 | Mainly Beta | Sandwich | Lipoxygenase-1 | PLAT/LH2 domain | CATH (4.3.0) |
A | 1.20.245.10 | Mainly Alpha | Up-down Bundle | Lipoxygenase-1 | domain 5 | CATH (4.3.0) |
A | 3.10.450.60 | Alpha Beta | Roll | Nuclear Transport Factor 2 | Chain: A, | CATH (4.3.0) |
B | 2.60.60.20 | Mainly Beta | Sandwich | Lipoxygenase-1 | PLAT/LH2 domain | CATH (4.3.0) |
B | 1.20.245.10 | Mainly Alpha | Up-down Bundle | Lipoxygenase-1 | domain 5 | CATH (4.3.0) |
B | 3.10.450.60 | Alpha Beta | Roll | Nuclear Transport Factor 2 | Chain: A, | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00305 | Lipoxygenase (Lipoxygenase) | Lipoxygenase | - | Domain | |
PF01477 | PLAT/LH2 domain (PLAT) | PLAT/LH2 domain | This domain is found in a variety of membrane or lipid associated proteins. It is called the PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology) domain. The known structure of pancreatic lipase shows this domain bind ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR020834 | Lipoxygenase, conserved site | Conserved Site | |
IPR001885 | Lipoxygenase, mammalian | Family | |
IPR013819 | Lipoxygenase, C-terminal | Domain | |
IPR001024 | PLAT/LH2 domain | Domain | |
IPR042062 | Lipoxygenase, vertebrates, PLAT domain | Domain | |
IPR036392 | PLAT/LH2 domain superfamily | Homologous Superfamily | |
IPR036226 | Lipoxigenase, C-terminal domain superfamily | Homologous Superfamily | |
IPR000907 | Lipoxygenase | Family | |
IPR020833 | Lipoxygenase, iron binding site | Binding Site |
Pharos: Disease Associations Pharos Homepage Annotation
Membrane Protein Annotation: OPM OPM Database Homepage
Chains | External Link | Type | Class | Superfamily | Family |
---|---|---|---|---|---|
OPM | Monotopic/peripheral | All alpha monotopic/peripheral | Lipoxygenase | Lipoxygenases |
Membrane Protein Annotation: mpstruc mpstruc Database Homepage
Chains | Resource Link | Group | Subgroup | Protein |
---|---|---|---|---|
mpstruc | MONOTOPIC MEMBRANE PROTEINS | Lipoxygenases | 5-Lipoxygenase |