3R10

Crystal structure of NYSGRC enolase target 200555, a putative dipeptide epimerase from Francisella philomiragia : Mg complex

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3r10a2	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Enolase C-terminal domain-like	automated matches	automated matches	(Francisella philomiragia subsp. philomiragia ATCC 25017 ) [TaxId: 484022 ],	SCOPe (2.08)
A	d3r10a1	Alpha and beta proteins (a+b)	Enolase N-terminal domain-like	Enolase N-terminal domain-like	automated matches	automated matches	(Francisella philomiragia subsp. philomiragia ATCC 25017 ) [TaxId: 484022 ],	SCOPe (2.08)
A	d3r10a4	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Francisella philomiragia subsp. philomiragia ATCC 25017 ) [TaxId: 484022 ],	SCOPe (2.08)
A	d3r10a3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Francisella philomiragia subsp. philomiragia ATCC 25017 ) [TaxId: 484022 ],	SCOPe (2.08)
B	d3r10b2	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Enolase C-terminal domain-like	automated matches	automated matches	(Francisella philomiragia subsp. philomiragia ATCC 25017 ) [TaxId: 484022 ],	SCOPe (2.08)
B	d3r10b1	Alpha and beta proteins (a+b)	Enolase N-terminal domain-like	Enolase N-terminal domain-like	automated matches	automated matches	(Francisella philomiragia subsp. philomiragia ATCC 25017 ) [TaxId: 484022 ],	SCOPe (2.08)
B	d3r10b4	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Francisella philomiragia subsp. philomiragia ATCC 25017 ) [TaxId: 484022 ],	SCOPe (2.08)
B	d3r10b3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Francisella philomiragia subsp. philomiragia ATCC 25017 ) [TaxId: 484022 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	MR_MLE_N	e3r10A1	A: a+b two layers	X: Enolase-N/ribosomal protein	H: Enolase N-terminal domain-like (From Topology)	T: Enolase N-terminal domain-like	F: MR_MLE_N	ECOD (1.6)
A	MR_MLE_C_1	e3r10A2	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: MR_MLE_C_1	ECOD (1.6)
B	MR_MLE_N	e3r10B1	A: a+b two layers	X: Enolase-N/ribosomal protein	H: Enolase N-terminal domain-like (From Topology)	T: Enolase N-terminal domain-like	F: MR_MLE_N	ECOD (1.6)
B	MR_MLE_C_1	e3r10B2	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: MR_MLE_C_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.390.10	Alpha Beta	2-Layer Sandwich	Enolase-like	domain 1	CATH (4.3.0)
A	3.20.20.120	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Enolase-like C-terminal domain	CATH (4.3.0)
B	3.30.390.10	Alpha Beta	2-Layer Sandwich	Enolase-like	domain 1	CATH (4.3.0)
B	3.20.20.120	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Enolase-like C-terminal domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF02746	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain (MR_MLE_N)	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain	SCOP reports fold similarity with enolase N-terminal domain.	Domain
A, B	PF13378	Enolase C-terminal domain-like (MR_MLE_C)	Enolase C-terminal domain-like	This domain appears at the C-terminus of many of the proteins that carry the MR_MLE_N Pfam:PF02746 domain. EC:4.2.1.40.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Enzyme of enolase superfamily	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding isomerase activity racemase and epimerase activity catalytic activity racemase and epimerase activity, acting on amino acids and derivatives	metabolic process peptide metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR029065	Enolase C-terminal domain-like	Domain
A, B	IPR013341	Mandelate racemase/muconate lactonizing enzyme, N-terminal domain	Domain
A, B	IPR034603	Dipeptide epimerase	Family
A, B	IPR013342	Mandelate racemase/muconate lactonizing enzyme, C-terminal	Domain
A, B	IPR029017	Enolase-like, N-terminal	Homologous Superfamily
A, B	IPR036849	Enolase-like, C-terminal domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.