3VD5
E. coli (lacZ) beta-galactosidase (N460S)
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2B Superfamily | beta-Galactosidase/glucuronidase domain-like | 8055209 | 3002047 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | beta-Galactosidase/glucuronidase domain-like | 8055462 | 3002047 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | Galactose mutarotase-like | 8037659 | 3000035 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | galactose-binding domain-like | 8037655 | 3000087 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | (Trans)glycosidases | 8037663 | 3000313 | SCOP2B (2022-06-29) |
B [auth C] | SCOP2B Superfamily | galactose-binding domain-like | 8037655 | 3000087 | SCOP2B (2022-06-29) |
B [auth C] | SCOP2B Superfamily | Galactose mutarotase-like | 8037659 | 3000035 | SCOP2B (2022-06-29) |
B [auth C] | SCOP2B Superfamily | (Trans)glycosidases | 8037663 | 3000313 | SCOP2B (2022-06-29) |
B [auth C] | SCOP2B Superfamily | beta-Galactosidase/glucuronidase domain-like | 8055209 | 3002047 | SCOP2B (2022-06-29) |
B [auth C] | SCOP2B Superfamily | beta-Galactosidase/glucuronidase domain-like | 8055462 | 3002047 | SCOP2B (2022-06-29) |
C [auth D] | SCOP2B Superfamily | galactose-binding domain-like | 8037655 | 3000087 | SCOP2B (2022-06-29) |
C [auth D] | SCOP2B Superfamily | Galactose mutarotase-like | 8037659 | 3000035 | SCOP2B (2022-06-29) |
C [auth D] | SCOP2B Superfamily | beta-Galactosidase/glucuronidase domain-like | 8055209 | 3002047 | SCOP2B (2022-06-29) |
C [auth D] | SCOP2B Superfamily | (Trans)glycosidases | 8037663 | 3000313 | SCOP2B (2022-06-29) |
C [auth D] | SCOP2B Superfamily | beta-Galactosidase/glucuronidase domain-like | 8055462 | 3002047 | SCOP2B (2022-06-29) |
D [auth B] | SCOP2B Superfamily | beta-Galactosidase/glucuronidase domain-like | 8055209 | 3002047 | SCOP2B (2022-06-29) |
D [auth B] | SCOP2B Superfamily | beta-Galactosidase/glucuronidase domain-like | 8055462 | 3002047 | SCOP2B (2022-06-29) |
D [auth B] | SCOP2B Superfamily | Galactose mutarotase-like | 8037659 | 3000035 | SCOP2B (2022-06-29) |
D [auth B] | SCOP2B Superfamily | (Trans)glycosidases | 8037663 | 3000313 | SCOP2B (2022-06-29) |
D [auth B] | SCOP2B Superfamily | galactose-binding domain-like | 8037655 | 3000087 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | Glyco_hydro_2_N | e3vd5A13 | A: beta sandwiches | X: jelly-roll | H: Concanavalin A-like | T: Galactose-binding domain-like | F: Glyco_hydro_2_N | ECOD (1.6) |
A | Glyco_hydro_2 | e3vd5A15 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: Glyco_hydro_2 | ECOD (1.6) |
A | DUF4981 | e3vd5A14 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: DUF4981 | ECOD (1.6) |
A | Bgal_small_N | e3vd5A12 | A: beta sandwiches | X: Glycosyl hydrolase domain-like | H: supersandwich (From Topology) | T: supersandwich | F: Bgal_small_N | ECOD (1.6) |
A | Glyco_hydro_2_C | e3vd5A11 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: Glyco_hydro_2_C | ECOD (1.6) |
B [auth C] | Glyco_hydro_2_N | e3vd5C13 | A: beta sandwiches | X: jelly-roll | H: Concanavalin A-like | T: Galactose-binding domain-like | F: Glyco_hydro_2_N | ECOD (1.6) |
B [auth C] | Glyco_hydro_2 | e3vd5C15 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: Glyco_hydro_2 | ECOD (1.6) |
B [auth C] | DUF4981 | e3vd5C14 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: DUF4981 | ECOD (1.6) |
B [auth C] | Bgal_small_N | e3vd5C12 | A: beta sandwiches | X: Glycosyl hydrolase domain-like | H: supersandwich (From Topology) | T: supersandwich | F: Bgal_small_N | ECOD (1.6) |
B [auth C] | Glyco_hydro_2_C | e3vd5C11 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: Glyco_hydro_2_C | ECOD (1.6) |
C [auth D] | Glyco_hydro_2_N | e3vd5D13 | A: beta sandwiches | X: jelly-roll | H: Concanavalin A-like | T: Galactose-binding domain-like | F: Glyco_hydro_2_N | ECOD (1.6) |
C [auth D] | Glyco_hydro_2 | e3vd5D15 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: Glyco_hydro_2 | ECOD (1.6) |
C [auth D] | DUF4981 | e3vd5D14 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: DUF4981 | ECOD (1.6) |
C [auth D] | Bgal_small_N | e3vd5D12 | A: beta sandwiches | X: Glycosyl hydrolase domain-like | H: supersandwich (From Topology) | T: supersandwich | F: Bgal_small_N | ECOD (1.6) |
C [auth D] | Glyco_hydro_2_C | e3vd5D11 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: Glyco_hydro_2_C | ECOD (1.6) |
D [auth B] | Glyco_hydro_2_N | e3vd5B13 | A: beta sandwiches | X: jelly-roll | H: Concanavalin A-like | T: Galactose-binding domain-like | F: Glyco_hydro_2_N | ECOD (1.6) |
D [auth B] | Glyco_hydro_2 | e3vd5B15 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: Glyco_hydro_2 | ECOD (1.6) |
D [auth B] | DUF4981 | e3vd5B14 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: DUF4981 | ECOD (1.6) |
D [auth B] | Bgal_small_N | e3vd5B12 | A: beta sandwiches | X: Glycosyl hydrolase domain-like | H: supersandwich (From Topology) | T: supersandwich | F: Bgal_small_N | ECOD (1.6) |
D [auth B] | Glyco_hydro_2_C | e3vd5B11 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: Glyco_hydro_2_C | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
A, B [auth C], C [auth D], D [auth B] | PF02836 | Glycosyl hydrolases family 2, TIM barrel domain (Glyco_hydro_2_C) | Glycosyl hydrolases family 2, TIM barrel domain | This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities. | Domain |
A, B [auth C], C [auth D], D [auth B] | PF00703 | Glycosyl hydrolases family 2 (Glyco_hydro_2) | Glycosyl hydrolases family 2 | This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities. | Domain |
A, B [auth C], C [auth D], D [auth B] | PF02837 | Glycosyl hydrolases family 2, sugar binding domain (Glyco_hydro_2_N) | Glycosyl hydrolases family 2, sugar binding domain | This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities and has a jelly-roll fold. The domain binds the sugar moiety during the sugar-hydrolysis reaction. | Domain |
A, B [auth C], C [auth D], D [auth B] | PF16353 | Beta-galactosidase, domain 4 (LacZ_4) | Beta-galactosidase, domain 4 | This entry represents domain 4 found in beta-galactosidase [1] and it is organised in a jelly-roll type barrel (Rutkiewicz-Krotewicz M. et al. Crystals 2018, 8(1), 13, https://doi.org/10.3390/cryst8010013). | Domain |
A, B [auth C], C [auth D], D [auth B] | PF02929 | Beta galactosidase small chain (Bgal_small_N) | Beta galactosidase small chain | This domain comprises the small chain of dimeric beta-galactosidases EC:3.2.1.23. This domain is also found in single chain beta-galactosidase. | Domain |