Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad3vd5a2 All beta proteins Immunoglobulin-like beta-sandwich beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain beta-Galactosidase, domains 2 and 4 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Ad3vd5a1 All beta proteins Galactose-binding domain-like Galactose-binding domain-like beta-Galactosidase/glucuronidase, N-terminal domain beta-Galactosidase (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Ad3vd5a5 All beta proteins Supersandwich Galactose mutarotase-like beta-Galactosidase, domain 5 beta-Galactosidase, domain 5 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Ad3vd5a3 Alpha and beta proteins (a/b) TIM beta/alpha-barrel (Trans)glycosidases beta-glycanases beta-Galactosidase, domain 3 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
B [auth C]d3vd5c2 All beta proteins Immunoglobulin-like beta-sandwich beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain beta-Galactosidase, domains 2 and 4 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
B [auth C]d3vd5c1 All beta proteins Galactose-binding domain-like Galactose-binding domain-like beta-Galactosidase/glucuronidase, N-terminal domain beta-Galactosidase (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
B [auth C]d3vd5c5 All beta proteins Supersandwich Galactose mutarotase-like beta-Galactosidase, domain 5 beta-Galactosidase, domain 5 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
B [auth C]d3vd5c3 Alpha and beta proteins (a/b) TIM beta/alpha-barrel (Trans)glycosidases beta-glycanases beta-Galactosidase, domain 3 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
C [auth D]d3vd5d2 All beta proteins Immunoglobulin-like beta-sandwich beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain beta-Galactosidase, domains 2 and 4 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
C [auth D]d3vd5d1 All beta proteins Galactose-binding domain-like Galactose-binding domain-like beta-Galactosidase/glucuronidase, N-terminal domain beta-Galactosidase (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
C [auth D]d3vd5d5 All beta proteins Supersandwich Galactose mutarotase-like beta-Galactosidase, domain 5 beta-Galactosidase, domain 5 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
C [auth D]d3vd5d3 Alpha and beta proteins (a/b) TIM beta/alpha-barrel (Trans)glycosidases beta-glycanases beta-Galactosidase, domain 3 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
D [auth B]d3vd5b2 All beta proteins Immunoglobulin-like beta-sandwich beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain beta-Galactosidase, domains 2 and 4 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
D [auth B]d3vd5b1 All beta proteins Galactose-binding domain-like Galactose-binding domain-like beta-Galactosidase/glucuronidase, N-terminal domain beta-Galactosidase (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
D [auth B]d3vd5b5 All beta proteins Supersandwich Galactose mutarotase-like beta-Galactosidase, domain 5 beta-Galactosidase, domain 5 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
D [auth B]d3vd5b3 Alpha and beta proteins (a/b) TIM beta/alpha-barrel (Trans)glycosidases beta-glycanases beta-Galactosidase, domain 3 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055209 3002047 SCOP2B (2022-06-29)
ASCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055462 3002047 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyGalactose mutarotase-like 8037659 3000035 SCOP2B (2022-06-29)
ASCOP2B Superfamilygalactose-binding domain-like 8037655 3000087 SCOP2B (2022-06-29)
ASCOP2B Superfamily(Trans)glycosidases 8037663 3000313 SCOP2B (2022-06-29)
B [auth C]SCOP2B Superfamilygalactose-binding domain-like 8037655 3000087 SCOP2B (2022-06-29)
B [auth C]SCOP2B SuperfamilyGalactose mutarotase-like 8037659 3000035 SCOP2B (2022-06-29)
B [auth C]SCOP2B Superfamily(Trans)glycosidases 8037663 3000313 SCOP2B (2022-06-29)
B [auth C]SCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055209 3002047 SCOP2B (2022-06-29)
B [auth C]SCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055462 3002047 SCOP2B (2022-06-29)
C [auth D]SCOP2B Superfamilygalactose-binding domain-like 8037655 3000087 SCOP2B (2022-06-29)
C [auth D]SCOP2B SuperfamilyGalactose mutarotase-like 8037659 3000035 SCOP2B (2022-06-29)
C [auth D]SCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055209 3002047 SCOP2B (2022-06-29)
C [auth D]SCOP2B Superfamily(Trans)glycosidases 8037663 3000313 SCOP2B (2022-06-29)
C [auth D]SCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055462 3002047 SCOP2B (2022-06-29)
D [auth B]SCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055209 3002047 SCOP2B (2022-06-29)
D [auth B]SCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055462 3002047 SCOP2B (2022-06-29)
D [auth B]SCOP2B SuperfamilyGalactose mutarotase-like 8037659 3000035 SCOP2B (2022-06-29)
D [auth B]SCOP2B Superfamily(Trans)glycosidases 8037663 3000313 SCOP2B (2022-06-29)
D [auth B]SCOP2B Superfamilygalactose-binding domain-like 8037655 3000087 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AGlyco_hydro_2_Ne3vd5A13 A: beta sandwichesX: jelly-rollH: Concanavalin A-likeT: Galactose-binding domain-likeF: Glyco_hydro_2_NECOD (1.6)
AGlyco_hydro_2e3vd5A15 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: Glyco_hydro_2ECOD (1.6)
ADUF4981e3vd5A14 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: DUF4981ECOD (1.6)
ABgal_small_Ne3vd5A12 A: beta sandwichesX: Glycosyl hydrolase domain-likeH: supersandwich (From Topology)T: supersandwichF: Bgal_small_NECOD (1.6)
AGlyco_hydro_2_Ce3vd5A11 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Glyco_hydro_2_CECOD (1.6)
B [auth C]Glyco_hydro_2_Ne3vd5C13 A: beta sandwichesX: jelly-rollH: Concanavalin A-likeT: Galactose-binding domain-likeF: Glyco_hydro_2_NECOD (1.6)
B [auth C]Glyco_hydro_2e3vd5C15 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: Glyco_hydro_2ECOD (1.6)
B [auth C]DUF4981e3vd5C14 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: DUF4981ECOD (1.6)
B [auth C]Bgal_small_Ne3vd5C12 A: beta sandwichesX: Glycosyl hydrolase domain-likeH: supersandwich (From Topology)T: supersandwichF: Bgal_small_NECOD (1.6)
B [auth C]Glyco_hydro_2_Ce3vd5C11 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Glyco_hydro_2_CECOD (1.6)
C [auth D]Glyco_hydro_2_Ne3vd5D13 A: beta sandwichesX: jelly-rollH: Concanavalin A-likeT: Galactose-binding domain-likeF: Glyco_hydro_2_NECOD (1.6)
C [auth D]Glyco_hydro_2e3vd5D15 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: Glyco_hydro_2ECOD (1.6)
C [auth D]DUF4981e3vd5D14 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: DUF4981ECOD (1.6)
C [auth D]Bgal_small_Ne3vd5D12 A: beta sandwichesX: Glycosyl hydrolase domain-likeH: supersandwich (From Topology)T: supersandwichF: Bgal_small_NECOD (1.6)
C [auth D]Glyco_hydro_2_Ce3vd5D11 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Glyco_hydro_2_CECOD (1.6)
D [auth B]Glyco_hydro_2_Ne3vd5B13 A: beta sandwichesX: jelly-rollH: Concanavalin A-likeT: Galactose-binding domain-likeF: Glyco_hydro_2_NECOD (1.6)
D [auth B]Glyco_hydro_2e3vd5B15 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: Glyco_hydro_2ECOD (1.6)
D [auth B]DUF4981e3vd5B14 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: DUF4981ECOD (1.6)
D [auth B]Bgal_small_Ne3vd5B12 A: beta sandwichesX: Glycosyl hydrolase domain-likeH: supersandwich (From Topology)T: supersandwichF: Bgal_small_NECOD (1.6)
D [auth B]Glyco_hydro_2_Ce3vd5B11 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Glyco_hydro_2_CECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A2.60.120.260 Mainly Beta Sandwich Jelly Rolls Galactose-binding domain-likeCATH (4.3.0)
A2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
A3.20.20.80 Alpha Beta Alpha-Beta Barrel TIM Barrel GlycosidasesCATH (4.3.0)
A2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase Chain A, domain 5CATH (4.3.0)
B [auth C]2.60.120.260 Mainly Beta Sandwich Jelly Rolls Galactose-binding domain-likeCATH (4.3.0)
B [auth C]2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
B [auth C]3.20.20.80 Alpha Beta Alpha-Beta Barrel TIM Barrel GlycosidasesCATH (4.3.0)
B [auth C]2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase Chain A, domain 5CATH (4.3.0)
C [auth D]2.60.120.260 Mainly Beta Sandwich Jelly Rolls Galactose-binding domain-likeCATH (4.3.0)
C [auth D]2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
C [auth D]3.20.20.80 Alpha Beta Alpha-Beta Barrel TIM Barrel GlycosidasesCATH (4.3.0)
C [auth D]2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase Chain A, domain 5CATH (4.3.0)
D [auth B]2.60.120.260 Mainly Beta Sandwich Jelly Rolls Galactose-binding domain-likeCATH (4.3.0)
D [auth B]2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
D [auth B]3.20.20.80 Alpha Beta Alpha-Beta Barrel TIM Barrel GlycosidasesCATH (4.3.0)
D [auth B]2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase Chain A, domain 5CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A,
B [auth C],
C [auth D],
D [auth B]
PF02836Glycosyl hydrolases family 2, TIM barrel domain (Glyco_hydro_2_C)Glycosyl hydrolases family 2, TIM barrel domainThis family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.Domain
A,
B [auth C],
C [auth D],
D [auth B]
PF00703Glycosyl hydrolases family 2 (Glyco_hydro_2)Glycosyl hydrolases family 2This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.Domain
A,
B [auth C],
C [auth D],
D [auth B]
PF02837Glycosyl hydrolases family 2, sugar binding domain (Glyco_hydro_2_N)Glycosyl hydrolases family 2, sugar binding domainThis family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities and has a jelly-roll fold. The domain binds the sugar moiety during the sugar-hydrolysis reaction.Domain
A,
B [auth C],
C [auth D],
D [auth B]
PF16353Beta-galactosidase, domain 4 (LacZ_4)Beta-galactosidase, domain 4This entry represents domain 4 found in beta-galactosidase [1] and it is organised in a jelly-roll type barrel (Rutkiewicz-Krotewicz M. et al. Crystals 2018, 8(1), 13, https://doi.org/10.3390/cryst8010013).Domain
A,
B [auth C],
C [auth D],
D [auth B]
PF02929Beta galactosidase small chain (Bgal_small_N)Beta galactosidase small chainThis domain comprises the small chain of dimeric beta-galactosidases EC:3.2.1.23. This domain is also found in single chain beta-galactosidase.Domain

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A,
B [auth C],
C [auth D],
D [auth B]
IPR032312Beta-galactosidase, domain 4Domain
A,
B [auth C],
C [auth D],
D [auth B]
IPR017853Glycoside hydrolase superfamilyHomologous Superfamily
A,
B [auth C],
C [auth D],
D [auth B]
IPR006101Glycoside hydrolase, family 2Family
A,
B [auth C],
C [auth D],
D [auth B]
IPR004199Beta galactosidase small chain/ domain 5Domain
A,
B [auth C],
C [auth D],
D [auth B]
IPR008979Galactose-binding-like domain superfamilyHomologous Superfamily
A,
B [auth C],
C [auth D],
D [auth B]
IPR006102Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwichDomain
A,
B [auth C],
C [auth D],
D [auth B]
IPR036156Beta-Galactosidase/glucuronidase domain superfamilyHomologous Superfamily
A,
B [auth C],
C [auth D],
D [auth B]
IPR006104Glycosyl hydrolases family 2, sugar binding domainDomain
A,
B [auth C],
C [auth D],
D [auth B]
IPR013783Immunoglobulin-like foldHomologous Superfamily
A,
B [auth C],
C [auth D],
D [auth B]
IPR006103Glycoside hydrolase family 2, catalytic domainDomain
A,
B [auth C],
C [auth D],
D [auth B]
IPR023232Glycoside hydrolase, family 2, active siteActive Site
A,
B [auth C],
C [auth D],
D [auth B]
IPR023230Glycoside hydrolase, family 2, conserved siteConserved Site
A,
B [auth C],
C [auth D],
D [auth B]
IPR023933Glycoside hydrolase, family 2, beta-galactosidaseFamily
A,
B [auth C],
C [auth D],
D [auth B]
IPR014718Glycoside hydrolase-type carbohydrate-bindingHomologous Superfamily
A,
B [auth C],
C [auth D],
D [auth B]
IPR050347Bacterial Beta-galactosidaseFamily
A,
B [auth C],
C [auth D],
D [auth B]
IPR011013Galactose mutarotase-like domain superfamilyHomologous Superfamily