Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyLysozyme-like 8066613 3001879 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyLysozyme-like 8066613 3001879 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ATransglye3vmtA2 A: a+b complex topologyX: Lysozyme-like (From Homology)H: Lysozyme-likeT: Lysozyme-likeF: TransglyECOD (1.6)
BTransglye3vmtB2 A: a+b complex topologyX: Lysozyme-like (From Homology)H: Lysozyme-likeT: Lysozyme-likeF: TransglyECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF00912Transglycosylase (Transgly)Transglycosylase- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
Monofunctional glycosyltransferase

Structure Motif Annotation: Mechanism and Catalytic Site Atlas M-CSA Database Homepage

ChainsEnzyme NameDescriptionCatalytic Residues
Peptidoglycan glycosyltransferase  M-CSA #970

Bacterial peptidoglycan glycosyltransferases (PGT) catalyse the polymerization of peptidoglycan (lipid II) into linear glycan chains, which is an essential part of peptidoglycan biosynthesis. It uses lipid II precursors to synthesize glycan chains of the peptidoglycan, the polymeric layer in the cell wall of bacteria. PGT inhibition leads to bacterial cell wall lysis, making it an important topic of research.

Defined by 4 residues: GLU:A-94 [auth A-100]GLY:A-125 [auth A-131]SER:A-126 [auth A-132]GLN:A-130 [auth A-136]
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Explore in 3DM-CSA Motif Definition
EC: 2.4 (PDB Primary Data)