3EHW
Human dUTPase in complex with alpha,beta-imido-dUTP and Mg2+: visualization of the full-length C-termini in all monomers and suggestion for an additional metal ion binding site
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d3ehwa_ | All beta proteins | beta-clip | dUTPase-like | automated matches | automated matches | human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
B | d3ehwb_ | All beta proteins | beta-clip | dUTPase-like | automated matches | automated matches | human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
C | d3ehwc_ | All beta proteins | beta-clip | dUTPase-like | automated matches | automated matches | human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
D [auth X] | d3ehwx_ | All beta proteins | beta-clip | dUTPase-like | automated matches | automated matches | human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
E [auth Y] | d3ehwy_ | All beta proteins | beta-clip | dUTPase-like | automated matches | automated matches | human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
F [auth Z] | d3ehwz_ | All beta proteins | beta-clip | dUTPase-like | automated matches | automated matches | human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2 Family | dUTPase-like | 8028685 | 4002970 | SCOP2 (2022-06-29) |
A | SCOP2 Superfamily | dUTPase-like | 8041064 | 3001957 | SCOP2 (2022-06-29) |
B | SCOP2B Superfamily | dUTPase-like | 8041064 | 3001957 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | dUTPase-like | 8041064 | 3001957 | SCOP2B (2022-06-29) |
D [auth X] | SCOP2B Superfamily | dUTPase-like | 8041064 | 3001957 | SCOP2B (2022-06-29) |
E [auth Y] | SCOP2B Superfamily | dUTPase-like | 8041064 | 3001957 | SCOP2B (2022-06-29) |
F [auth Z] | SCOP2B Superfamily | dUTPase-like | 8041064 | 3001957 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | dUTPase | e3ehwA1 | A: beta barrels | X: beta-clip | H: dUTPase-like (From Topology) | T: dUTPase-like | F: dUTPase | ECOD (1.6) |
B | dUTPase | e3ehwB1 | A: beta barrels | X: beta-clip | H: dUTPase-like (From Topology) | T: dUTPase-like | F: dUTPase | ECOD (1.6) |
C | dUTPase | e3ehwC1 | A: beta barrels | X: beta-clip | H: dUTPase-like (From Topology) | T: dUTPase-like | F: dUTPase | ECOD (1.6) |
D [auth X] | dUTPase | e3ehwX1 | A: beta barrels | X: beta-clip | H: dUTPase-like (From Topology) | T: dUTPase-like | F: dUTPase | ECOD (1.6) |
E [auth Y] | dUTPase | e3ehwY1 | A: beta barrels | X: beta-clip | H: dUTPase-like (From Topology) | T: dUTPase-like | F: dUTPase | ECOD (1.6) |
F [auth Z] | dUTPase | e3ehwZ1 | A: beta barrels | X: beta-clip | H: dUTPase-like (From Topology) | T: dUTPase-like | F: dUTPase | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 2.70.40.10 | Mainly Beta | Distorted Sandwich | Deoxyuridine 5'-Triphosphate Nucleotidohydrolase | Chain A | CATH (4.3.0) |
B | 2.70.40.10 | Mainly Beta | Distorted Sandwich | Deoxyuridine 5'-Triphosphate Nucleotidohydrolase | Chain A | CATH (4.3.0) |
C | 2.70.40.10 | Mainly Beta | Distorted Sandwich | Deoxyuridine 5'-Triphosphate Nucleotidohydrolase | Chain A | CATH (4.3.0) |
D [auth X] | 2.70.40.10 | Mainly Beta | Distorted Sandwich | Deoxyuridine 5'-Triphosphate Nucleotidohydrolase | Chain A | CATH (4.3.0) |
E [auth Y] | 2.70.40.10 | Mainly Beta | Distorted Sandwich | Deoxyuridine 5'-Triphosphate Nucleotidohydrolase | Chain A | CATH (4.3.0) |
F [auth Z] | 2.70.40.10 | Mainly Beta | Distorted Sandwich | Deoxyuridine 5'-Triphosphate Nucleotidohydrolase | Chain A | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00692 | dUTPase (dUTPase) | dUTPase | dUTPase hydrolyses dUTP to dUMP and pyrophosphate. | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR008181 | Deoxyuridine triphosphate nucleotidohydrolase | Family | |
IPR033704 | dUTPase, trimeric | Domain | |
IPR036157 | dUTPase-like superfamily | Homologous Superfamily | |
IPR029054 | dUTPase-like | Domain |